currently, hematopoietic stem cell transplantation (hsct) is the only curative option for patients with beta-thalassemia major, but liver iron overload in these patients will not decrease and hepatic fibrosis may still progress despite successful hsct. liver biopsy samples were taken from 14 patients (out of 25 patients) who underwent hsct. all patients met three criteria: negative hcv antibody...

Despite recent growing research interest on ERP research, the understanding on ERP induced exhaustion is still limited. This study examines how the pace of change of ERP functionalities and interface causes exhaustion in workplace. For this purpose, we conducted an investigation on 128 ERP users from two different organizations in Bangladesh. We extended theory of technostress by integrating pa...

This work shows that overload handling will always be necessary regardless of future improvements in hardware performance. The most difficult part when constructing a fair overload handling system is that in today’s internet infrastructure one can no more identify a single client by its IP address. The proposed solution is based on so called Proof-Of-Work functions. Thus, a client willing to se...

Wireless networks are currently experiencing more overload situations than their wireline counterparts because of explosive mobile traffic growth, unpredictable traffic behavior, service differentiated traffic shedding, etc. Even though extensive research work on network overload control in general is going on, the economic aspect of the overload problem has received very little attention. Mana...

iron chelation therapy is used to reduce iron overload development due to its deposition in various organs such as liver and heart after regular transfusion. in this review, different iron chelators implicated in treatment of iron overload in various clinical conditions have been evaluated using more up-to-date studies focusing on these therapeutic agents. deferoxamine, deferiprone and deferasi...

This work reports a facile sonochemical route in the synthesis of nano particle of deferasirox for the first time. One application of nanotechnology is in improvement of available treatments for various diseases. Deferasirox (ICL670 or Exjade) is a tridentate chelating agent for removing transfusion overload iron in thalassemia patients. In the present work, deferasirox was prepared in nano size...

BACKGROUND Inflammatory arthritis impairs participation in societal roles. Role overload arises when the demands by a given role set exceed the resources; time and energy, to carry out the required tasks. The present study examines the association between role overload and disease outcomes in early inflammatory arthritis (EIA). METHODS Patients (n = 104) of 7.61 months mean duration of inflam...

Web servers often experience overload situations due to the extremely bursty nature of Internet traffic, popular online events or malicious attacks. Such overload situations significantly affect performance and may result in lost revenue as reported by the recent denial of service attacks. Overload control schemes are well researched and understood in telecommunication systems. However, their u...