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An almost unbiased estimator using known value of some population parameter(s) is proposed. Under simple random sampling without replacement (SRSWOR) scheme the expressions for bias and mean square error (MSE) are derived. Numerical illustrations are given.

The adaptation of cardiovascular and thermoregulatory responses to ozone (O3) was examined by repeated exposure of electrocardiographic (ECG) electrode- and thermistor sensor-implanted rats to O3 for 4 consecutive days (8 hrs/day). Circadian rhythms of heart rate (HR) and abdominal core temperature (Tco) were disrupted on the first and second O3 exposure days in a concentration dependent manner...

To date, no consensus exists on the key factors for diagnosing advanced Parkinson disease (APD). To obtain consensus on the definition of APD, we performed a prospective, multicenter, Spanish nationwide, 3-round Delphi study (CEPA study). An ad hoc questionnaire was designed with 33 questions concerning the relevance of several clinical features for APD diagnosis. In the first-round, 240 neurol...

Health-related quality of life (HRQOL) instruments are sometimes used without explicit understanding of which HRQOL domains are important to a given population. In this study, we sought to elicit an importance hierarchy among 27 HRQOL domains (derived from the general population) via a best-worst scaling survey of the population in Singapore, and to determine whether these domains were consiste...

Unsaturated eight-membered lactones undergo decarboxylative and non-decarboxylative transannular Ireland-Claisen rearrangement reactions, to give substituted vinylcyclobutanes. A formal synthesis of (±)-grandisol is described.

OBJECTIVES The aim of this study was to investigate potential statistical relationships between black tea consumption and key health indicators in the world. The research question is: Does tea consumption is correlated with one or more epidemiological indicators? DESIGN Ecological study using a systematic data-mining approach in which the unit of the analysis is a population of one country. ...

PURPOSE To report our experience of dosimetric comparison of IPSA and manual plans, with a focus on the use of help structures (HS) during optimization. MATERIAL AND METHODS 33 patients who underwent MR image-based HDR intracavitary-brachytherapy for cervix cancer based on GYN-ESTRO recommendations were selected for evaluation. Tandem/ovoid (T/O) and Vienna applicators were used. HS of diamet...

A 53 year-old man who had been suffering from left leg pain had relief to some degree with conservative treatment. Fifteen days later he had another painful episode and was hospitalized for physical therapy. Acute paraparesia developed on the tenth day after admission. On neurosurgical consultation there was paraparesia which was prominent distally. both patella and Achilles reflexes were aboli...

Sixteen patients with cystic fibrosis were treated with conventional physiotherapy aided by an assistant. The results were compared with those produced by physiotherapy using the forced expiration technique cleared more sputum in less time than conventional physiotherapy. A sputum in less time than conventional physiotherapy. A second study showed that an assistant did not further improve the r...