Excessive microglial activation often contributes to inflammation-mediated neurotoxicity in the ischemic penumbra during the acute stage of ischemic stroke. Toll-like receptor 4 (TLR4) has been reported to induce microglial activation via the NF-κB pathway. Isoflurane preconditioning (IP) can provide neuroprotection and inhibit microglial activation. In this study, we investigated the roles of ...

Two studies found that individuals high in private self-consciousness provide self-reports of greater reliability across time than individuals low in private self-consciousness. In addition, Study 2 found that a successful manipulation of self-awareness did not affect test-retest reliability of self-reports among Ss either high or low in private self-consciousness. The hypothesis that individua...

Background: Acute kidney injury (AKI) is the most common and life-threatening systemic complication of rhabdomyolysis. Inflammation plays an important role in the development of rhabdomyolysis-induced AKI. This study aimed to investigate the kidney model of AKI caused by rhabdomyolysis to verify the role of macrophage Toll-like receptor 4/nuclear factor-kappa B (TLR4/NF-κB) signaling pathway. ...

This report discusses various aspects of undergraduate cross-registration procedures, including the dimensions, values, roles and functions, basic assumptions, and facilitating and encouragment of crow: registration. Dimensions of cross-registration encompass financial exchange, eligibility, program limitations, type of grade and credit; extent of participation, academic requirements, and appro...

We investigated the mechanism of the Toll-like receptor 4- (TLR4-) mediated PI3K/AKT/GSK-3β signaling pathway in rat hepatocytes apoptosis induced by LPS. The cultured rat hepatocytes were treated with LPS alone or first pretreated with TLR4 inhibitor, AKT inhibitor, and GSK-3β inhibitor, respectively, and then stimulated with the same dose of LPS. Cell viability, cell apoptotic rate, and apopt...

objective: in this study, psychometric qualities of multidimensional perfectionism scale (mps) were evaluated. methods: persian version of perfectionism inventory was completed by 48 adults (24 females and 24 males). the sample was selected by cluster random sampling from sarcheshmeh adult inhabitants. reliability of the scale was assessed by calculating cronbach's alpha coefficient. then ...

assessment of relationship between self-efficacy and self- care in copd patients     abedi ha [1] , salimi s [2] , feizi a [3] , safari vaghasloo s [4] *     received: 17 sep, 2011 accepted: 27 nov, 2011     abstract   background & aims : given the importance of the copd and role of different factors in self-care behaviors of copd patients, this study have been conducted to determine the relati...

background personal, behavioral, psychological, social and psychological factors disorders can influence the outbreak of psychological disorders. the study aimed to examine the prevalence and severity of depression and relationship with self-efficacy in diabetic patients of fereydan and chadegan cities. methods: the research was a descriptive-analytic and cross-sectional, which studies 403 pati...