Paget's Disease in the population younger than 50 years is uncommon. We present a 29 year-old male with thyroid cancer and monostotic Paget's Disease of the spine mimicking bone metastases. The patient who was suffering from severe back pain, had increased osteoblastic activity on bone scan consistent with the suspicious lesion defined on MRI and conventional X-ray. Despite the positive radiolo...

DESCRIPTION A 54-year-old patient underwent right radical nephrectomy for what was then diagnosed as a Stage-II (T2bN0M0) renal cell carcinoma (RCC). Four months after surgery, the patient reported of pelvic pain and had a rising serum alkaline-phosphatase level. The tecnetium-99 mmethylene-diphosphate (Tc99m-MDP) bone scan then demonstrated a focus of uptake in the right ischium, corresponding...

A 25-year-old patient with osteosarcoma of the right distal femur underwent a bone scintigraphy with Tc-99m methylene diphosphonate (MDP). Whole-body bone scan revealed extensive metastatic disease in the abdominal region. Abdominal computerized tomography confirmed the presence of ascites and calcified masses on the greater omentum and peritoneal surfaces. Here we describe a case of unusual me...

radionuclide therapy is widely used as an effective modality in the management of bone pain. the main indication for this treatment is symptomatic bone metastases, confirmed by bone scintigraphy. we present a case of small cell lung cancer (sclc) stage t4n2m1b, with a good metabolic response to systemic therapy and radiotherapy of the primary tumor and locoregional disease, which became metabol...

This case is described of an eleven-month-old infant with lower limbs swelling and the left elbow skeletal malformation following a fall. The radionuclide bone scan was performed to exclude bone infection or congenital skeletal anomaly. The images unexpectedly showed multiple increased radioactive foci throughout the whole body. It was a strong probability of child abuse. All lesions are readil...

Imatinib mesylate is an effective, small-molecule, selective tyrosine kinase inhibitor, which inhibits BCR-ABL in patients with chronic myeloid leukemia, c-kit gastrointestinal tumor (GIST), and platelet-derived growth factors hypereosinophilic syndrome. Above all, bone marrow necrosis a rare complication of imatinib usage. If newly developed increased opacity lesions are seen metastatic GIST, ...

Various models of the human chest have been developed to evaluate injury risks or to assess innovative safety systems. In the frame of the EU FP7 project THOMO, a protocol has been established to determine relevant parameters of the human ribcage. This original method has been developed by combining CT-scan, 3D laser scan and μCT-scan to determine precisely the internal rib architecture. The ma...