BACKGROUND Weight loss improves cardiovascular risk factors and "quality of life". Most therapeutic approaches fail to induce a sustained weight loss and most individuals undergo weight regain. In this paper the comprehensive design of the "MAINTAIN" study, all assessments as well as the one year lifestyle intervention will be outlined in detail. METHODS/DESIGN One-center randomized controlle...

We performed a systematic review of the behavioral lifestyle intervention trials conducted in the United States published between 1990 and 2011 that included a maintenance phase of at least six months, to identify intervention features that promote weight loss maintenance in African American women. Seventeen studies met the inclusion criteria. Generally, African American women lost less weight ...

Background: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in women of reproductive age, affecting 7% of this population. Although not entirely understood, the etiology of PCOS is closely linked to obesity and abdominal adiposity that are considered to worsen the clinical presentation, particularly menstrual irregularities and hyperandrogenism. Lifestyle mo...

Evidence has suggested that self-weighing may be beneficial for weight control in adults, but few studies have independently assessed the contribution of this behavior to weight loss. This study experimentally tested daily self-weighing and visual feedback (the Caloric Titration Method (CTM)) as a weight loss and weight loss maintenance intervention over 2 years. 162 overweight individuals were...

BACKGROUND Although the serum adiponectin level is inversely correlated to body mass index and closely associated with obesity and related diseases, neither the impact of weight loss on the adiponectin level nor other factors that might influence the adiponectin level during weight loss intervention are well documented. OBJECTIVE The objective of the study is to assess the change in the serum...

www.thelancet.com Published online May 3, 2017 http://dx.doi.org/10.1016/S0140-6736(17)31042-5 1 In 2014, 52% of adults globally were overweight or obese. Lifestyle programmes, which target improved diet and exercise practices, reliably produce clinically relevant weight changes and are viable options that can reach multiple populations and be delivered on a large scale. Consequently, these lif...

PURPOSE/OBJECTIVES To investigate whether quality of life (QOL) assessed before weight loss intervention predicts weight loss and, in turn, what the effect of weight loss is on QOL measures after 12 months in early-stage breast cancer survivors. DESIGN A clinical trial of a weight loss intervention in breast cancer survivors. SETTING Community-wide recruitment in Detroit, MI. SAMPLE 39 br...