BACKGROUND Stepped wedge randomised trial designs involve sequential roll-out of an intervention to participants (individuals or clusters) over a number of time periods. By the end of the study, all participants will have received the intervention, although the order in which participants receive the intervention is determined at random. The design is particularly relevant where it is predicted...

We have measured pulmonary artery (PA) and left ventricular diastolic pressures (LVDP) in patients with acute myocardial infarction to establish the relationships of PA pressure to LVDP. Paired determinations for the various parameters showed (mean difference in mm Hg): left ventricular end-diastolic pressure (LVEDP )LVDP pre-a + 7.9, P <0.001; LVEDP-mean PA wedge + 6.0, P < 0.001; mean PA wedg...

Sandbox modeling is used to study the deformation of accretionary wedges caused by the subduction of oceanic ridges. The first experiment incorporates a massive ridge within a sand wedge. The wedge thickens and shortens when the forward propagation f the basal decollement ceases. The wedge thickening results in taper change, reactivation of preexisting thrusts, and retreat of the frontal part o...

We have measured pulmonary artery (PA) and left ventricular diastolic pressures (LVDP) in patients with acute myocardial infarction to establish the relationships of PA pressure to LVDP. Paired determinations for the various parameters showed (mean difference in mm Hg): left ventricular end-diastolic pressure (LVEDP )LVDP pre-a + 7.9, P <0.001; LVEDP-mean PA wedge + 6.0, P < 0.001; mean PA wedg...

BACKGROUND Wedge filters can be used as missing tissue compensators or wedge pairs to alter the shape of isodose curves so that two beams can be angled with a small hinge angle at a target volume without creating a hotspot. AIM In this study the dosimetric properties of Varian Enhanced Dynamic Wedge (EDW) and physical wedges (PW) were analyzed and compared. MATERIALS AND METHODS Ionometric ...

Radiographs of 110 patients who had undergone 120 high tibial osteotomies (60 closed-wedge, 60 open-wedge) were assessed for posterior tibial slope before and after operation, and before removal of the hardware. In the closed-wedge group the mean slope was 5.7 degrees (SD 3.8) before and 2.4 degrees (SD 3.9) immediately after operation, and 2.4 degrees (SD 3.4) before removal of the hardware. I...

In this paper we study the wedge disclination within the elastoplastic defect theory. Using the stress function method we found exact analytical solutions for all characteristic fields of a straight wedge disclination in a cylinder. The elastic stress, elastic strain, elastic bend-twist, displacement and rotation have no singularities at the disclination line. We found a modified stress functio...