The generalized structure of deoxyribonucleic acid (DNA) is based on the rules topological spaces. DNA recombination one most important processes within DNA, as it essential in pharmaceutical industry well gene therapy. In this paper, we are discussing relationship between rough sets, nano spaces (N), Z open (N) and recombination. We also created a new mapping using properties process. Further,...

We report the first study of the biological effect of fulvestrant on ER positive clinical breast cancer using sequential biopsies through to progression. Thirty-two locally/systemically advanced breast cancers treated with first-line fulvestrant (250 mg/month) were biopsied at therapy initiation, 6 weeks, 6 months and progression and immunohistochemically-analyzed for Ki67, ER, EGFR and HER2 ex...

Let R = (R,<,+, ·, . . . ) be a non-valuational weakly o-minimal real closed field, I a definable convex open subset of R and f : I → R a definable function. We prove that {x ∈ I : f ′(x) exists in R} is definable and f ′ is definable if f is differentiable.

HOPs (heat shock protein 70 (HSP70)-heat shock protein 90 (HSP90) organizing proteins) are a highly conserved family of cytosolic cochaperones. In a recent study we showed that HOP3, a member of the HOP family in Arabidopsis, plays an essential role during endoplasmic reticulum (ER) stress in plants. Interestingly, we also demonstrated that AtHOP3 interacts with binding immunoglobulin protein (...

Yeast Yip1p is a member of a conserved family of transmembrane proteins that interact with Rab GTPases. Previous studies have also indicated a role for Yip1p in the biogenesis of ER-derived COPII transport vesicles. In this report we describe the identification and characterization of the uncharacterized open reading frame YER074W-A as a novel multi-copy suppressor of the thermosensitive yip1-4...

It has been suggested that the estrogenicity of PAHs could contribute to their carcinogenic effects via increased tissue-specific cell proliferation. Both benzo[a]pyrene (BaP) and benz[a]anthracene (BaA) are known to weakly activate estrogen receptor (ER)-dependent reporter constructs. In this study, several other PAHs, including fluorene, fluoranthene, pyrene, chrysene, phenanthrene and anthra...

In this paper we introduce intuitionistic fuzzy contra regular weakly generalized open mappings and intuitionistic fuzzy contra regular weakly generalized closed mappings. We investigate some of their properties.