In human breast cancer, estrogen receptor (ER) status of the tumor has prognostic and therapeutic significance. However, facilities to study ER are not widely available to us. We postulated that if there is a correlation between histologic grade and ER status of invasive ductal carcinoma (IDC), it may help predict the ER status of the tumor. Of 8 4 cases of breast carcinoma referred to the ...

The ubiquitous inositol 1,4,5-trisphosphate (InsP(3)) receptor (InsP(3)R) Ca(2+) release channel plays a central role in the generation and modulation of intracellular Ca(2+) signals, and is intricately regulated by multiple mechanisms including cytoplasmic ligand (InsP(3), free Ca(2+), free ATP(4-)) binding, posttranslational modifications, and interactions with cytoplasmic and endoplasmic ret...

primary-like and weakly primary-like submodules are two new generalizations of primary ideals from rings to modules. in fact, the class of primary-like submodules of a module lie between primary submodules and weakly primary-like submodules properly.  in this note, we show that these three classes coincide when their elements are submodules of a multiplication module and satisfy the primeful pr...

In this paper we prove existence the common fixed point with different conditions for $alpha-psi$-contractive mappings. And generalize weakly Zamfirescu map in to modified weakly Zamfirescu map.

Over the last few years, an increased awareness of endocrine disrupting chemicals (EDCs) and their potential to affect wildlife and humans has produced a demand for practical screening methods to identify endocrine activity in a wide range of environmental and industrial chemicals. While it is clear that in vivo methods will be required to identify adverse effects produced by these chemicals, i...

in this paper we prove existence the common fixed point with different conditions for $alpha-psi$-contractive mappings. and generalize weakly zamfirescu map in to modified weakly zamfirescu map.

BACKGROUND Endocrine-disrupting chemicals (EDCs) influence the activity of estrogen receptors (ERs) and alter the function of the endocrine system. However, the diversity of EDC effects and mechanisms of action are poorly understood. OBJECTIVES We examined the agonistic activity of EDCs through ERα and ERβ. We also investigated the effects of EDCs on ER-mediated target genes. METHODS HepG2 ...

Estrogenic industrial compounds such as bisphenol A (BPA) and nonylphenol typically bind estrogen receptor (ER) alpha and ERBeta and induce transactivation of estrogen-responsive genes/reporter genes, but their potencies are usually greater than or equal to 1,000-fold lower than observed for 17Beta-estradiol. Risk assessment of estrogenic compounds on the basis of their potencies in simple repo...

banach contraction principle has been generalized in different spaces by mathematicians over the years. mustafa and sims [18] proposed a new class of generalized metric spaces, which are called as g-metric spaces. in this type of spaces a non-negative real number is assigned to every triplet of elements. many mathematicians studied extensively various results on g-metric spaces by using the con...