Angiopoietins (Angs) are endothelium-selective ligands that exert most of their actions through the Tie-2 receptor. It is widely accepted that Ang-1 promotes the structural integrity of blood vessels and exhibits anti-inflammatory properties. In contrast, the role of Ang-2 remains less clear because it has been shown to behave as a Tie-2 agonist or antagonist under different experimental condit...

Who talks with whom in national policymaking? How do lobbyists allocate their social resources to best receive information? And how does network position condition which lobbyists get access? We analyze communication networks among lobbyists and government actors in national politics. We begin by wedding rational choice models to network analysis with a formal analysis of lobbyists’ choice of c...

Social capital and social support are two key constructs in the study of social networks and health. Despite their importance, little research has sought to examine the characteristics of those social ties by which individuals access social capital and support resources. Network diversity - a key structural feature in accessing social capital - refers to a person's broad but generally weak and ...

Background : Controlling global epidemics in the real world and accelerating information propagation in the artificial world are of great significance, which have activated an upsurge in the studies on networked spreading dynamics. Lots of efforts have been made to understand the impacts of macroscopic statistics (e.g., degree distribution and average distance) and mesoscopic structures (e.g., ...

OBJECTIVE To investigate the involvement of Tie-1 and Tie-2, receptor tyrosine kinases required for angiogenesis, in synovial proliferation and angiogenesis of rheumatoid arthritis (RA). METHODS Synovial tissues from 10 patients with RA and three control subjects were analysed by double immunohistochemistry and reverse transcriptase polymerase chain reaction (RT-PCR). RESULTS Expression of ...

abstractthis study focused mainly on the shifts of the grammatical cohesion in texts translated from english into persian. it aimed to identify the grammatical cohesive devices (gcds) in st and tt separately, based on halliday and hassn's model (1976), determine the number of occurrences of gcds in two texts and finally, illustrate types of shifts of grammatical cohesion and strategies used in ...

TIE is a receptor tyrosine kinase expressed in both mature endothelial cells and their precursors, as well as in some hematopoietic cells. Mouse embryos homozygous for a disrupted Tie allele die at midgestation due to impaired endothelial cell integrity and resulting hemorrhage. Here we have performed chimeric analysis to study further the function of the murine TIE in the development of embryo...

A receptor tyrosine kinase (RTK), TIE (tyrosine kinase that contains immunoglobulin-like loops and epidermal growth factor [EGF] homology domains), is expressed in vascular endothelial and hematopoietic cells. We generated monoclonal antibodies (MoAbs) against the extracellular domain of TIE and a polyclonal antibody against the TIE carboxyterminus and used them to analyze expression of TIE in ...

the effect of magnetic field on the liquid-liquid equilibrium of two ternary systems (water + acetic acid + butyl acetate and water + acetic acid + dimethyl succinate) at 298.15 k under atmospheric pressure was investigated. the results obtained show that the strength of the magnetic field (0.02 t) affects the solubility of acetic acid in the used organic solvents. distribution coefficients and...