Acute chest syndrome (ACS) of sickle cell disease (SCD) is characterized pathologically by vaso-occlusive processes that result from abnormal interactions between sickle red blood cells (RBCs), white blood cells (WBCs) and/or platelets, and the vascular endothelium. One potential mechanism of vascular damage in ACS is by generation of oxygen-related molecules, such as superoxide (O2-), hydrogen...

BACKGROUND In a phase III trial, older patients with acute myeloid leukemia (N=485) received decitabine or treatment choice (supportive care or cytarabine). This post hoc analysis examined whether baseline renal and hepatic function and white blood cell (WBC) counts predicted response. METHODS Baseline WBCs and renal and liver function markers were tabulated for responders/nonresponders. RE...

in this paper we present a method related to extracting white blood cells (wbcs) from blood microscopic figures and recognizing them and counting each kind of wbcs. in this method, first we extract the white blood cells from other blood cells by rgb color system's help. in continuance, by using the features of each kind of globules and their color scheme, we extract a normalized feature vector,...

In the human body, white blood cells (WBCs) are crucial immune that help in early detection of a variety illnesses. Determination number WBCs can be used to diagnose conditions such as hematological, immunological, and autoimmune diseases, well AIDS leukemia. However, conventional method classifying counting is time-consuming, laborious, potentially erroneous. Therefore, this paper presents com...

The ability to isolate fetal nucleated red blood cells (NRBCs) from the maternal circulation makes possible prenatal genetic analysis without the need for diagnostic procedures that are invasive for the fetus. Such isolation requires antibodies specific to fetal NRBCs. To generate a panel of antibodies to antigens present on fetal NRBCs, a new type of nonimmune phage antibody library was genera...

The size discrepancy between leukocytes [white blood cells (WBCs)] and pulmonary capillaries requires WBCs to deform. We investigated the persistence of this deformation on cells leaving the capillary bed and the role played by the cytoskeleton. Isolated rabbit lungs were perfused in situ via the pulmonary artery with effluent fractions collected from the left ventricle. Washout curves from cel...

An investigation of the electrochemical activity of human white blood cells (WBC) for biofuel cell (BFC) applications is described. WBCs isolated from whole human blood were suspended in PBS and introduced into the anode compartment of a proton exchange membrane (PEM) fuel cell. The cathode compartment contained a 50 mM potassium ferricyanide solution. Average current densities between 0.9 and ...

BACKGROUND Exposure of blood products to gamma irradiation is currently the standard of care in the prevention of transfusion-associated graft-versus-host disease (TA-GVHD). Regulatory, technical, and clinical challenges associated with the use of gamma irradiators are driving efforts to develop alternatives. Pathogen reduction methods were initially developed to reduce the risk of microbial tr...

It is difficult to building deep learning algorithms for identifying chronic diseases. One of the must difficulties facing system diagnosing leukemia irregular shape and twisted nucleus in white blood cells (WBCs) without cleaning segmentation by Appling filters. Moreover, it challenge identify classify WBC at once time which considered essential step diagnosing. This paper proposed only based ...