Circulating tumor cells (CTCs) in peripheral blood have been recognized as a general biomarker for diagnosing cancer and providing guidance for personalized treatments. Yet due to their rarity, the challenge for their clinical utility lies in the efficient isolation while avoiding the capture of other non-targeted white blood cells (WBCs). In this paper, a wavy-herringbone (HB) microfluidic chi...

The analytical solution is obtained for a semi-infinite linear elastic solid with a sinusoidal, “wavy” surface profile subject to applied strain. The amplitude A of a deformed wavy surface is related to the initial amplitude A0 and the applied strain a through the simple expression A A0 1 a . This relation is confirmed independently by finite element analyses and experimental measurements of st...

Computer simulations of two-phase gas-liquid pipe flow cases have been performed with the commercial code STAR-CD using the VOF method and the results are illustrated in this paper. Computed pressure losses for stratified flow and stratified-wavy flow and time-averaged liquid levels are compared against measured data, showing good agreement with the experimental data. To achieve these results, ...

A parallel embedded boundary approach for large-eddy simulations of turbulent flows with complex geometries and dynamically moving boundaries on fixed orthogonal grids is presented. The underlying solver is based on a second-order fractional step method on a staggered grid. The boundary conditions on an arbitrary immersed interface are satisfied via second-order local reconstructions. The paral...

Neurofibromas commonly involve peripheral nervous system. Isolated neurofibroma of vagina is very rare tumor and usually associated with Von Recklinghausen's disease. Vulva is the most frequent location of neurofibroma of genital tract followed by clitoris and labia. We present a rare case of neurofibroma of vaginal wall presented as vaginal cyst in a 52 year old female with no history of any o...

This paper presents an experimental study of imperfection insensitive composite wavy cylindrical shells subject to axial compression. A fabrication technique for making cylindrical shells with intricate shape of cross-sections has been developed. A photogrammetry technique to measure the geometric imperfections has also been developed. The behavior of the wavy shells under axial compression was...

A NEW SPECIES OF COCCIDIAN (PROTOZOA Apicomplexa: Eimeriidae) obtained from rheas, Rhea americana, is reported in Brazil. Oocysts of Isospora rheae sp. nov. are spherical to subspheroidal, measuring 22.6 × 21.0 µm, and have a double and smooth wall that is approximately 1.7 µm thick. The micropyle, oocyst residuum and polar granule are absent. Sporocysts are slightly ovoid, measuring 13.9 × 9.6...

The probability density function of single-point velocity fluctuations in turbulence is studied systematically using Fourier coefficients in the energy-containing range. In ideal turbulence where energy-containing motions are random and independent, the Fourier coefficients tend to Gaussian and independent of each other. Velocity fluctuations accordingly tend to Gaussian. However, if energy-con...

Natural convection in cubical enclosure with hot surface geometry and partial partitions has been analyzed. The geometry is a cube with wavy hot surface (three undulations) and three partitions. The investigation has been performed for different partitions lengths and Rayleigh number while the Prandtl number kept constant. This problem is solved by using the partial differential equations which...

Hydrodynamic forces in bioreactors can decisively influence extracellular matrix deposition in engineered cartilage constructs. In the present study, the reduced fluid shear, high-axial mixing environment provided by a wavy-walled bioreactor was exploited in the cultivation of cartilage constructs using polyglycolic acid scaffolds seeded with bovine articular chondrocytes. Increased growth as d...