نتایج جستجو برای: warfarin reversal
تعداد نتایج: 44044 فیلتر نتایج به سال:
BACKGROUND Anticoagulation with warfarin should be stopped 4-6 days before invasive procedures to avoid bleeding complications. Despite this routine, some patients still have high International Normalized Ratio (INR) values on the day of surgery and the procedure may be cancelled. We sought to identify easily available clinical characteristics that may influence the rate of normalization of pro...
ABSTRACT Atrial fibrillation (AF) is the most common cardiac arrhythmia in the U.S. Anticoagulation is recommended for stroke prevention in AF patients with intermediate-to-high stroke risk (i.e., patients with a CHADS2 score of 1 or greater). Warfarin was previously the only option for oral anticoagulation in these patients, but three new oral anticoagulants have become available as alternativ...
Wider use of oral anticoagulants has led to an increasing frequency of warfarin-related intracerebral hemorrhage (ICH). The high early mortality of approximately 50% has remained stable in recent decades. In contrast to spontaneous ICH, the duration of bleeding is 12 to 24 hours in many patients, offering a longer opportunity for intervention. Treatment varies widely, and optimal therapy has ye...
OBJECTIVES This cross-sectional survey explored the characteristics and outcomes of direct oral anticoagulant (DOAC)-associated nontraumatic intracerebral hemorrhages (ICHs) by analyzing a large nationwide Japanese discharge database. METHODS We analyzed data from 2,245 patients who experienced ICHs while taking anticoagulants (DOAC: 227; warfarin: 2,018) and were urgently hospitalized at 621...
A trial fibrillation (AF) is the most common cardiac arrhythmia. It was estimated to affect up to 6.1 million Americans in 2010, and since AF is more common with increasing age, it is predicted to affect 12.1 million in the United States by 2030. AF increases the risk of stroke 5-fold across all age groups, and AF-related stroke incidence ranges from <1% to >20% per year in the absence of antic...
A trial fibrillation (AF) is the most common cardiac arrhythmia. It was estimated to affect up to 6.1 million Americans in 2010, and since AF is more common with increasing age, it is predicted to affect 12.1 million in the United States by 2030. AF increases the risk of stroke 5-fold across all age groups, and AF-related stroke incidence ranges from <1% to >20% per year in the absence of antic...
BACKGROUND AND PURPOSE Anticoagulation-related intracerebral hemorrhage (ICH) is often fatal, and rapid reversal of anticoagulation is the most appealing strategy currently available for treatment. We sought to determine whether particular emergency department (ED) interventions are effective in reversing coagulopathy and improving outcome. METHODS Consecutive patients with warfarin-related I...
V itamin K antagonists (VKAs), such as warfarin, are widely used for prevention and treatment of arterial and venous thrombosis. Although oral or intravenous vitamin K and fresh frozen plasma are often used to reverse the antico-agulant effects of warfarin in patients who are bleeding, this approach has important limitations. Restoration of hemosta-sis with vitamin K relies on the hepatic synth...
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