Evolutionary ecological theory predicts that sleep-wake state tradeoffs may be related to local environmental conditions and should therefore correlate to alterations in behavioral life history strategies. It was predicted that firefighters who slept more and reported better quality sleep on average would exhibit lower impulsivity inclinations related to slower life history trajectories. UPPS i...

The formation of orographic wakes and vortices is studied within the context of numerically simulated viscous flow with uniform basic-state wind and stability past elongated free-slip ridges. The viscosity and thermal diffusivity are sufficiently large that the onset of small-scale turbulence is suppressed. It is found in Part I of this study that wake formation in the viscous flow is closely t...

In this paper, we have simulated the excitation of wake fields in the interaction of an intensive laser pulses having Half-Sine and Gaussian time envelopes with a fully ionized cold plasma using particle in cell (PIC) method. We investigated the dependency of wake filed amplitude to different laser and plasma parameters such as laser wavelength, pulse duration and electron number density. In ad...

Multiple ascending neurotransmitter systems participate in the regulation of behavioral state. For example, noradrenergic, cholinergic, and serotonergic systems increase EEG and, in some cases, behavioral indices of arousal. The extent to which dopaminergic systems exert a similar activating influence on behavioral state remains unclear. The current studies examined the wake-promoting actions o...

PURPOSE/OBJECTIVES To update the state of the science on sleep-wake disturbances in adult patients with cancer, focusing on insomnia in the areas of prevalence, mechanisms and models, measurement, interventions, and implications for practice, health policy, education, and research. DATA SOURCES Published articles, books, book chapters, MEDLINE, CINAHL, and PsycINFO computerized databases. D...

RATIONALE Long-term intermittent hypoxia (LTIH) exposure in adult mice, modeling oxygenation patterns of moderate-severe obstructive sleep apnea, results in lasting hypersomnolence and is associated with nitration and oxidation injuries in many brain regions, including wake-active regions. OBJECTIVES We sought to determine if LTIH activates inducible nitric oxide synthase (iNOS) in sleep/wake...

Histaminergic neurons play an important role in the regulation of sleep-wake behavior through histamine H(1) receptors (H(1)R). Blockade of the histamine H(3) receptor (H(3)R) is proposed to induce wakefulness by regulating the release of various wake-related transmitters, not only histamine. In the present study, we characterized sleep-wake cycles of H(1)R knockout (KO) mice and their arousal ...

BACKGROUND Wake-up tests may be necessary during surgery for kypho-scoliosis to ensure that spinal function remains intact. It is difficult to predict the time when patients can respond to a verbal command. We evaluated the effectiveness of the bispectral index (BIS) and its relation to patients' levels of consciousness in wake-up tests during desflurane and sevoflurane anesthesia. METHODS Ei...

Recent findings in infant rats suggest that the preoptic area (POA) and/or basal forebrain (BF) contribute to developmental changes in sleep and wake organization between postnatal day 2 (P2) and P9. To examine the contributions of these forebrain areas to sleep and wakefulness, separate lesions of the POA or BF, or combined lesions (POA + BF), were performed at P9, and precollicular transectio...