The risk of neurological diseases increases with age. In WAG/Rij rat model of absence epilepsy, the incidence of epileptic spike-wave discharges is known to be elevated with age. Considering close relationship between epileptic spike-wave discharges and physiologic sleep spindles, it was assumed that age-dependent increase of epileptic activity may affect time-frequency characteristics of sleep...

A 2-yr study was conducted to evaluate 1) steers fed ad libitum high concentrate after weaning (CONC), or 2) steers grown on pasture for 82 d, followed by high-concentrate finishing (PAST), on the performance and carcass traits of 74 early-weaned (117 d of age) steers. Potential breed differences were evaluated using crossbred steers of three types: 1) 3/4 Angus x 1/4 Simmental (BRI), 2) 3/4 Si...

A 2-yr study was conducted to evaluate 1) steers fed ad libitum high concentrate after weaning (CONC), or 2) steers grown on pasture for 82 d, followed by high concentrate finishing (PAST) on the performance and carcass traits of 74 early weaned (117 d of age) steers. Potential breed differences were evaluated using steers of three different breed types: 1) 3⁄4 Angus x 1⁄4 Simmental (BRI), 2) 3...

Objective: In the last two decades, research on epigenetic mechanisms has expanded dramatically. Recent studies demonstrated that regulate epilepsy and epileptogenic pathologies. this study, we aimed to investigate changes in promoter methylation status of voltage-gated T-type calcium channel alpha 1 subunit G (CACNA1G) gene total histone deacetylase activity Wistar Albino Glaxo/Rijswijk (WAG/R...

Metallic nanoparticles are widely used in cosmetics, food products and textile industry. These particles are known to cause respiratory toxicity and epithelial inflammation. They are eventually released to aquatic environment necessitating toxicity studies in cells from respiratory organs of aquatic organisms. Hence, we have developed and characterized a new cell line, WAG, from gill tissue of ...

Direct spectroscopic evidence for a hydride bridge in the Ni-R form of [NiFe] hydrogenase has been obtained using iron-specific nuclear resonance vibrational spectroscopy (NRVS). The Ni-H-Fe wag mode at 675 cm(-1) is the first spectroscopic evidence for a bridging hydride in Ni-R as well as the first iron-hydride-related NRVS feature observed for a biological system. Although density function t...

This paper focuses on an event, the World Alternative Games (WAG), as a site for development and maintenance of community. The research shows how rural community uses its own interpretation space to create new activities, inspire collaborative promote tourism within particular locale. Drawing upon ethnographic undertaken at third edition WAG in 2016, it provides social constructivist account pa...

This paper describes the input specification language of the WAG Sentence Generation system. The input is described in terms of Halliday's (1978) three meaning components, ideational meaning (the propositional content to be expressed), interactional meaning (what the speaker intends the listener to do in making the utterance), and textual meaning (how the content is structured as a message, in ...

The present studies sought to determine the concentrations of endogenous kynurenic acid (KYNA) and to measure the activity of kynurenine aminotransferases (KAT) I and II in the discrete brain regions of 3- and 6-month old WAG/Rij rats, a genetic model of absence epilepsy. Analogues experiments were performed using age-matched ACI rats, which served as a non-epileptic control. The age-dependent ...

It is well accepted that absence epilepsy is not accompanied by structural brain abnormalities. In the present report, we challenged this view based on microscopic analysis of neocortex in a genetic model of absence epilepsy, WAG/Rij rats. Density of neurons and glial cells was measured in the motor, somatosensory and cingular cortical areas in epileptic WAG/Rij rats and in non-epileptic contro...