Pyridoxine (PN) is a metabolic precursor of pyridoxal phosphate that functions as a cofactor of many enzymes in amino acid metabolism. PN, pyridoxal, and pyridoxamine are collectively referred to as vitamin B6, and mammalian organisms depend on its uptake from the diet. In addition to the ability to use extracellular vitamin B6, most unicellular organisms are also capable of synthesizing PN to ...

VITAMIN B6 REQUIREMENTS IN MAN I rc 1934 Gyorgy1 reported experimental studies on the relation of a dietary factor to rat dermatitis and established this nutrient as a new member of the B-Cornplex, calling it vitamin B6. The vitamin subsequently isolated26 and synthesized was found to be 2 methyl-3 hydroxy-4, 5 hydroxy methyl pyridine and called pyridoxine.7 By means of an elegant series of exp...

BACKGROUND Bacterial meningitis caused by Streptococcus pneumoniae leads to death in up to 30% of patients and leaves up to half of the survivors with neurological sequelae. The inflammatory host reaction initiates the induction of the kynurenine pathway and contributes to hippocampal apoptosis, a form of brain damage that is associated with learning and memory deficits in experimental paradigm...

OBJECTIVE Our objective was to examine associations among plasma homocysteine concentrations (tHcy), the tHcy-cofactors (folate, vitamins B6 and B12), and multiple domains of cognitive performance, with statistical adjustment for possible confounds, including cardiovascular disease risk factors (CVD-RF) and cardiovascular disease (CVD). METHODS Subjects were 812 participants (58% women) of th...

The etiology of vitamin B(6) depletion in inflammation remains unknown. Hepatic vitamin B(6) decreased in adrenalectomized rats, and such reductions were restored by an acute muscle injection of a very high dose of glucocorticoids. We tested the hypothesis that long-term prednisolone treatment for treating inflammation restores vitamin B(6) status by induction of tissue B6 metabolic enzymes. Tw...

Objective. Comparing the effectiveness of vitamin B6 (40 mg twice daily) and ginger (250 mg four times daily) in treatment of pregnancy nausea. Methods. In a clinical trial in health centers of Qazvin University of Medical Sciences from November 2010 to February 2011 on pregnant mothers, the effects of vitamin B6 (40 mg twice daily) and ginger (250 mg four times daily) were evaluated in treatme...

Cereal Chem. 73(6):770-774 Analysis of different wheats and flours for vitamin B6 using water exin PN (0.9-2.7 nmol/g). Mean values (± standard deviations) were 5.0 ± tracts and reverse-phase high-performance liquid chromatography 1.8 nmol/g for total vitamin B6; 1.7 ± 0.5 nmol/g for PN; and 3.4 ± 1.8 revealed significant variation in content of pyridoxine (PN) and pyrinmollg for PNG. American ...

INTRODUCTION The differential diagnosis of neutropenia includes medications, infections, autoimmune diseases, and deficiencies of Vitamin B12 and folate. The association of Vitamin B6 deficiency with severe neutropenia is a rare finding. CASE PRESENTATION A 51-year-old Caucasian woman presented with fever and profound neutropenia (48 neutrophils/uL). Her clinical history included non-Hodgkin ...


 Nausea (nausea) and vomiting (emesis gravidarum) are normal symptoms often found in the first trimester of pregnancy. Almost 50-90% pregnant women experience nausea trimester. One pharmacological methods that can be used to treat pregnancy is consume pyridoxine (vitamin B6) non-pharmacological among them Ambon banana (Musa paradisiaca) which contains lots flavonoids vitamin B6 able overc...