BACKGROUND Lymphocytic gastritis (LG) is an uncommon entity with varying symptoms and endoscopic appearances. This condition, as well as two forms of H. pylori-negative gastritis [chronic active gastritis (CAG) and chronic inactive gastritis (CIG)], appears to be more common in patients with coeliac disease (CD) based on single-centred studies. AIM To compare the prevalence of LG, CAG and CIG...

Classical treatment for congenital toxoplasmosis is based on combination of sulfadiazine and pyrimethamine plus folinic acid. Due to teratogenic effects and bone marrow suppression caused by pyrimethamine, the establishment of new therapeutic strategies is indispensable to minimize the side effects and improve the control of infection. Previous studies demonstrated that enrofloxacin and toltraz...

Gestational trophoblastic disease (GTD) is a spectrum of cellular proliferations arising from the placental villous trophoblasts encompassing four main clinicopathologic forms : hydatidiform mole (complete and partial), invasive mole, choriocarcinoma and placental site trophoblastic tumor (PSTT). Placental site trophoblasic tumours (PSTT) are rare and usually diagnosed after dilatation and cure...

References BOYER, C.W. & HELFRICH, R.B. (1966) Adenoma of the duodenal bulb. American Journal of Roentology, 90, 753. BREMER, E.H., BATTAILE, W.G. & BULLE, P.H. (1968) Villous tumours of upper gastro-intestinal tract. American Journal of Gastroenterology, 50, 135. DAWSON, J.L. (1964) Leiomyoma of duodenum causing recurrent bleeding. Gut, 5, 184. DWYER, W.A. & O'BRIEN, R.F. (1970) Duodenal obstr...

Villous adenomas are benign lesions, which are difficult to interpret because of their malignancy potential. They have similar radiological findings to malignant lesions. Usually, villous adenomas are asymptomatic although they may cause rectal bleeding like malignant tumours. We present a case of giant villous adenoma to evaluate the contribution of its radiological features including double c...

This report presents the findings of TIL development from tumour biopsies of patients with bladder cancer. Analysis of tissue sections showed the presence of T cells in intra-epithelial layer in 8 of 12 cases investigated. In a larger group of patients, TILs were established from 7 of 20 cases and expansion of these cells in Interleukin-2 (IL-2) in the presence of conditioned medium (CM) r...

Many studies have documented that placental development is altered by a variety of environmental factors which alter placental bed blood flow and/or oxygen delivery. One of these is sustained weight-bearing exercise. The purpose of this investigation was to examine the effects of running throughout pregnancy on villous vascular development and cell proliferation by testing the null hypothesis t...

Branching morphogenesis (BM) of the chorionic villous tree is a crucial component of early placental formation. Fibroblast growth factors (FGFs), their receptor tyrosine kinase (RTK) and negative regulators like Sprouty (Spry) proteins are pivotal factors in the development of diverse branching organ systems. The aim of this study was to examine the effect of FGF10 and Sprouty 2 on BM of the ch...

AIM To quantify the presence of villous atrophy in endoscopic images for improved automation. METHODS There are two main categories of quantitative descriptors helpful to detect villous atrophy: (1) Statistical and (2) Syntactic. Statistical descriptors measure the small intestinal substrate in endoscope-acquired images based on mathematical methods. Texture is the most commonly used statisti...