................................................................................................................................III SVENSK SAMMANFATTNING...........................................................................................IV ACKNOWLEDGEMENTS ......................................................................................................V LIST OF APPENDED PAPERS.........

.............................................................................................................................. III ACKNOWLEDGMENTS ........................................................................................................... V TABLE OF CONTENTS .......................................................................................................... VII LIST OF FIG...

We have studied factor VII activation by measuring the ratio of factor VII clotting to coupled amidolytic activity (VIIc/VIIam) and cleavage of 125I-factor VII. In purified systems, a low concentration of Xa or a higher concentration of IXa rapidly activated 125I-factor VII, yielding a VIIc/VIIam ratio of 25 and similar gel profiles of heavy and light chain peaks of VIIa. On further incubation,...

........................................................................................................................................................ V ACKNOWLEDGEMENT............................................................................................................................... VII PUBLICATIONS .....................................................................................

A family with a peculiar defect of factor VII is described. The propositi, a brother and sister, were born of a nonconsanguineous marriage and presented a mild to moderate bleeding tendency since childhood (epistaxis, excessive bleeding after tooth extraction). The coagulation pattern was characterized by a mildly prolonged prothrombin time, normal partial thromboplastin time, and normal Stypve...

Abstract. A case of the matrix Kummer relation of Herz (1955) based on the Pearson VII type matrix model is derived in this paper. As a con- sequence, the polynomial Pearson VII configuration density is obtained and this sets the corresponding exact inference as a solvable aspect in shape theory. An application in postcode recognition, including a nu- merical comparison between the exact poly...

Syt VII is a Ca(2+) sensor that regulates lysosome exocytosis and plasma membrane repair. Because it lacks motifs that mediate lysosomal targeting, it is unclear how Syt VII traffics to these organelles. In this paper, we show that mutations or inhibitors that abolish palmitoylation disrupt Syt VII targeting to lysosomes, causing its retention in the Golgi complex. In macrophages, Syt VII is tr...

objective(s):to clarify the protective effects of cichorium glandulosum (cg) extracts on thioacetamide (taa)-induced rat hepatic fibrosis. materials and methods: the dry roots of cg were smashed and percolated with 95% ethanol, and the residual was prepared into petroleum ether extract (cg-v), ethyl acetate extract (cg-vi) and n-butyl alcohol extract (cg-vii). thirty-six wistar rats were random...

One pathway of blood coagulation, the extrinsic system, is initiated by a specific interaction between tissue factor, which is a membrane lipoprotein, and factor VII, one of the plasma coagulation factors. Factor VII was prepared from bovine plasma by adsorption onto and elution from BaSO(4). The eluate was chromatographed on DEAE-Sephadex and purified by preparative disc-gel electrophoresis. F...

The concurrency is classified into two types: structured concurrency and nonstructured concurrency. After showing that the nonstructured concurrency cannot be represented by the conventional notations in the Petri net language, a method to represent such concurrency by the language is proposed. The proposed method allows us to utilize the existing approaches for analyzing properties of a nonstr...