OBJECTIVES We aimed to compare the hemodynamic effects of right-atrial-paced (DDD) and right-atrialsensed (VDD) biventricular paced rhythm on cardiac resynchronization therapy (CRT). BACKGROUND Cardiac resynchronization therapy improves hemodynamics in patients with severe heart failure and left ventricular (LV) dyssynchrony. However, the impact of active right atrial pacing on resynchronizatio...

BACKGROUND AND PURPOSE Vitamin D deficiency (VDD) is a global health problem, which can lead to several pathophysiological consequences including cardiovascular diseases. Its impact on the cerebrovascular system is not well understood. The goal of the present work was to examine the effects of VDD on the morphological, biomechanical and functional properties of cerebral arterioles. METHODS Fo...

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. While the primary risk factor for COPD is cigarette smoke exposure, vitamin D deficiency has been epidemiologically implicated as a factor in the progressive development of COPD-associated emphysema. Because of difficulties inherent to studies involving multiple risk factors in the progression of...

Key circulating molecules that link vitamin D (VD) to pediatric obesity and its co-morbidities remain unclear. Using a proteomic approach, our objective was to identify key molecules in obese children dichotomized according to 25OH-vitamin D (25OHD) levels. A total of 42 obese children (M/F = 18/24) were divided according to their 25OHD3 levels into 25OHD3 deficient (VDD; n = 18; 25OHD<15 ng/ml...

Vitamin D deficiency (VDD) is common in women with and without polycystic ovary syndrome (PCOS) and may be associated with metabolic and endocrine disorders in PCOS. The aim of this meta-analysis is to assess the associations of serum vitamin D levels with metabolic and endocrine dysregulations in women with PCOS, and to determine effects of vitamin D supplementation on metabolic and hormonal f...

Changes in retinal geometric parameters predict risk and progression of diabetic retinopathy (DR). We have shown that vitamin D deficiency (VDD) is associated with DR. We hypothesized that VDD mediates changes in retinal geometric parameters. Retinal vascular geometric parameters were assessed using a semiautomated computer program in photographs from young people with type 1 diabetes (T1D) (n ...

The design of future large optical telescopes must take into account the wind-induced vibration of the telescope structure that is caused by large-scale flow structures and turbulence inside the telescope enclosure when the aperture in the enclosure dome is open. However, estimating the resulting degradation in image quality is difficult due to our relatively poor understanding of the flow insi...

Abstract. Ice crystals are mechanically and dielectrically anisotropic. They progressively align under cumulative deformation, forming an ice-crystal-orientation fabric that, in turn, impacts ice deformation. However, almost all the observations of from core analysis, its influence on flow is unclear. Here, we present a non-linear inverse approach to process co- cross-polarized phase-sensitive ...