Nicolaides-Baraitser syndrome (NCBRS) is a rare and well-recognized entity that was first described in 1993, with a prevalence that is currently not known. It is recognized as a distinctive entity, with some variability in its signs and symptoms. The most important characteristics include intellectual disability, peculiar facial features including sparse scalp hair, coarse facial features, low ...

This case report describes a 17-year-old patient with confirmed SARS-CoV-2 infection erosions of the vermilion lips and hard palate, circumferential erythematous periurethral glans penis, small vesicles on trunk upper extremities.

N the investigation of pigmentation among the lozenge series of pseudoalleles I in Drosophila melanogaster, the amount and distribution of red and brown pigments in the compound eyes of the lozenge mutants can be analyzed histologically by studying the genic effect on the two pigments separately. In an earlier report (CLAYTON 1957), the distribution of pigment in males of the lozenge mutants wa...

BACKGROUND Up-regulation of tryptophan (Trp) conversion into kynurenine (Kyn) and increased formation of down-stream metabolites of Kyn is one of the mechanisms of aging and neurodegenerative disorders. Kyn is an immediate precursor of kynurenic acid (KYNA), an antagonist to NMDA and α7nAChR receptors and activator of aryl hydrocarbon receptor. Increased formation of KYNA ameliorates neurodegen...

We have surveyed three natural populations of Drosophila ananassae for restriction map variation at the forked c f ) and vermilion (v ) loci, using 6-cutter restriction enzymes. Both loci are located in the centromeric region of the X chromosome. Two major conclusions can be drawn from the data. First, we found strong evidence for population subdivision, i .e . , significant differences in the ...

The vermilion rockfish complex consists of two distinct species, (Sebastes miniatus) and sunset (S. crocotulus) with clear haplotypic differences. Due to a one-way mitochondrial introgression from into high proportion (20–30%) fish haplotype are characterized as based on nuclear genotype (introgressed sunset, hereafter, introgressed). Here we examined differences in the distribution biological ...

UPPRESSION is the complete or partial restoration of the wild-type phenotype by one gene in the presence of another nonallelic mutant gene that alone causes a mutant phenotype. Intragenic “suppressors” have also been reported (CRICK, BARNETT, BRENNER and WATTS-TOBIN 1961; HELINSKI and YANOFSKY 1963) but the term “second site reversion” used by HELINSKI and YANOFSKY seems useful in distinguishin...