dried oleander leaves at single lethal dose of 110 mg/kg body weight were administered orally to fivenative female goats. clinical signs of toxicosis in goats began to appear about 1 hr after receiving theoleander and included abdominal pain, ruminal atony and tympany, frequent urination, bradycardia,tachycardia, tachyarrhythmia, depression, weakness and convulsive movement and death at the end...

BACKGROUND The anisotropy of cardiac tissue is a key determinant of 3D electric propagation and the stability of activation wave fronts in the heart. The electric properties of ventricular myocardium are widely assumed to be axially anisotropic, with activation propagating most rapidly in the myofiber direction and at uniform velocity transverse to this. We present new experimental evidence tha...

A 72-year-old female was found to have symptomatic hypertrophic obstructive cardiomyopathy associated with significant aortic stenosis. She severe left ventricular outflow tract obstruction, asymmetric septal hypertrophy, systolic anterior motion of the mitral valve leaflet, and regurgitation. also moderate stenosis that made obstruction even worse which patient progressively not responding med...

We measured indices of energy metabolism in tissue samples taken from the interventricular septum and left ventricular free wall of open-chest dogs under control conditions and after a 20-second period of no coronary inflow. The heart was paced at 150 beats/min, and arterial pressure was controlled by aortic constriction. Each tissue sample was divided into three transmural regions and analyzed...

Adrenomedullin (ADM) is a new member of a family of vasodilating and natriuretic peptides that plays an important role in cardiorenal regulation. This study was designed to establish the plasma, urinary, cardiac, and renal tissue concentrations and immunohistochemical localizations of ADM in normal dogs and dogs with experimental congestive heart failure (CHF) produced by rapid ventricular paci...

conclusions there is a significant increased incidence of mortality, prolonged hospitalization, and rehospitalization in symptomatic patients with severe tr. therefore, we recommend more aggressive approach toward tv repair or replacement in these patients regardless of pap and systolic function. results heart failure (50%) was the most cause of death. mean years of survival from diagnosis of s...

Introduction: Cardiac remodeling after myocardial infarction, is associated with progressive ventricular dysfunction and cardiovascular death. The purpose of this study was to examine the effect of endurance exercise training on morphological changes in rat heart tissue following experimental myocardial infarction. Materials and methods: Rats used in this experiment (8-10 weeks old, 235 &p...

A case of severe right ventricular obstruction caused by a huge aneurysmal tissue tag is described associated with a perimembranous ventricular septal defect with an infundibular extension. Angiograms and surgical inspection clearly showed that the ventricular septal defect extended into the outlet septum. The distinctive features of this case was the severity of the gradient related to the pec...

background: sickle-cell disease (scd) is an inherited hemoglobin childhood disorder, frequently complicated by pulmonary hypertension and cardiac involvement. cardiovascular events and complications are the leading cause of mortality and morbidity in patients with scd. tissue doppler imaging and the myocardial performance index (tei index), are simple indices for the assessment of the cardiac f...