In a correlative study between selected body-surface potential recordings and anatomic findings, multilead sets of high-fidelity, high-speed records from 128 persons were studied in connection with the results of our detailed postmortem dissections of their hearts. Attention was focused on high-frequency components (notching and slurring of the expanded QRS) as described by Langner. We found th...

Several studies have demonstrated that the natural course of hypertrophic cardiomyopathy can be variable, often unpredictable with high morbidity and mortality. Therefore, screening for potential cases and periodical evaluation of affected patients is compelling. The purpose of our study is to assess a relationship of the electrocardiographic finding of ST-segment elevation and/or abnormal Q wa...

We analyzed T1-weighted brain magnetic resonance imaging data of 100 cognitively normal elderly controls (NC), 127 cognitively normal Parkinson's disease (PD; PDCN) and 31 PD-associated mild cognitive impairment (PDMCI) subjects from the Norwegian ParkWest study. Using automated segmentation methods, followed by the radial distance technique and multiple linear regression we studied the effect ...

Left ventricular hypertrophy has been suggested to mediate the relation between hypertension and left atrial enlargement, with associated risks of atrial fibrillation and stroke. However, less is known about correlates of left atrial size in hypertensive patients with left ventricular hypertrophy. We assessed left atrial size by echocardiography in 941 hypertensive patients, age 55 to 80 (mean,...

Introduction: Hydrocephalus (HC) is a disease characterized by obstruction of cerebrospinal fluid (CSF) flow in either the lateral ventricles (noncommunicating) or subarachnoid space (communicating), resulting in an increase in ventricular size and a subsequent increase in intracranial pressure (ICP). Currently, magnetic resonance imaging or computed tomography assist in diagnosis, but these im...

A semiautomated computer analysis was developed to estimate fluid volumes in each hemicranium from computed tomography scans. The method was used to estimate total ventricular and sulcal fluid in 123 normal subjects aged 23-88 years. A wide range of normal values was found. The trend was for the estimated ventricular and sulcal fluid volumes to remain relatively constant until age 60 and then t...