background the early repolarization pattern (erp) has been considered a normal variant in electrocardiography (ecg) for a long time. nevertheless, increasing evidence has demonstrated its association with adverse outcomes. objectives the present study aimed to evaluate the prevalence of erp in the iranian general population and demonstrate its clinical and ecg correlates. methods a cross sectio...

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noncompaction of the ventricular myocardium is an embryonic cardiomyopathy that is increasingly being recognized. noncompaction of lv myocardium, right ventricular myocardium, or both can occur in isolation, in congenital heart diseases, in valvular heart diseases, in neuromuscular disorders, skeletal abnormalities and in endocrinologic abnormalities. clinical manifestations of ventricular non-...

The basic helix-loop-helix transcriptional repressor Hairy-related transcription factor 2 (Hrt2) is expressed in ventricular, but not atrial, cardiomyocytes, and in endothelial and vascular smooth muscle cells. Mice homozygous for a null mutation of Hrt2 die perinatally from a spectrum of cardiac abnormalities, raising questions about the specific functions of this transcriptional regulator in ...

Regional differences in cell size in the hearts of rats with and without cardiac hypertrophy were studied using isolated muscle cells. Isolated cardiac myocytes were prepared from left ventricular free wall inner and outer halves and the right ventricle of six male 12-week-old spontaneously hypertensive (SHR), Wistar-Kyoto (WKY) and Fischer-344 rats. In SHR, blood pressure was increased to 188 ...

conclusion the cv value correlated more closely with low lvef and more accurately indicated an enlarged heart than ca or ctr. this may be due to the fact that an anteroposterior measurement of heart size is included in the former but not the latter two measurements. these study results may help quantify left heart enlargement with greater accuracy than may be obtained from standard cxr. backgro...

introduction: cardiac complications, including heart failure, are the most important secondary ones of the thalassemia major disease, which manifests itself in adolescence and early adulthood. appropriate, low cost diagnostic tools available as well as knowing its related factors are the most important components of therapy in these patients, given the importance of these complications, or by e...

introduction: recent studies have shown acute cardioprotective effects of cyclosporine. the aim of the present study was to determine the protective role of cyclosporine on the model simulated the rotational nodal arrhythmia (avnrt) by using extracellular field potential recordings of isolated atrioventricular-node (av-node) of rabbit. methods: this study was performed on isolated double-perfus...

background there is the controversy concerning the main component of tobacco, which is responsible for its arrhythmogenesis. in addition, there is the lack of adequate information about the influence of combination of black tea and nicotine on heart rhythm. objectives this study aimed to examine whether pretreatment with black tea and nicotine could modulate the susceptibility to lethal ventric...