Background: Vascular endothelial growth factor (VEGF) is an angiogenic growth factor that is produced by different tissues, including the endometrium and ovary. VEGF is involved in many processes related to reproductive physiology, including angiogenesis, which is essential for implantation and placentation. It has been suggested that VEGF may be the angiogenic factor responsible for the implan...

background: alpha-thalassemia syndrome includes a group of hereditary anemia in which expression of alpha globin chains is decreased or absent. impaired rbc in patients with thalassemia causes vessel involvement and endothelial cell vessel disturbance. vascular endothelial growth factor (vegf) is the most important regulator for endothelial cell proliferation. so, the aim of this study is to co...

objective(s):although previous studies have confirmed the beneficial effects of human umbilical cord matrix stem cell (hucm) transplantation post myocardial infarction (mi), but this stem cell resource has no potential to induce angiogenesis. in order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hucm ...

Objective(s): To investigate the effect of miR-103 on the angiogenesis of ischemic stroke rats via targeting vascular endothelial growth factor (VEGF) at the molecular level. Materials and Methods: Rat models had received the middle cerebral artery occlusion (MCAO) or sham operation before grouping, and cell models of oxygen-glucose deprivation (OGD) were performed. FITC-dextran, matrigel, and ...

Background: Vascular endothelial growth factor A (VEGFA) plays a key role in angiogenesis during human placenta formation and its abnormal expressions have been reported in placental tissues of women with recurrent miscarriage (RM). Objective: The aim of this study was to evaluate the correlation of polymorphism of VEGF1154 G/A gene in RM and In Vitro Fertiliz...

background: oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. the role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. vascular endothelial growth factor (vegf) is an important regulator of angiogenesis. we aimed to evaluate the serum level of vegf in patients with oral lichen planus compared with normal in...

background:diabetic retinopathy (dr) is a sight-threatening microvascular complication of diabetes in which the vascular endothelium is damaged due to oxidative stress and inflammation, and vitreous vegf concentration becomes elevated. the aim of the present study was to assess the association of dr with genetic variations of the mnsod, a major antioxidant enzyme, and vegf, an important mediato...