INTRODUCTION More women are delaying child-bearing such that gynaecologists can no longer resort as frequently to definitive treatments, such as a hysterectomy, in the management of uterine fibroids. A review of newer conservative medical, radiological and surgical therapies and minimal access approaches to the organ-preserving myomectomy operation are discussed. MATERIALS AND METHODS Data fr...

BACKGROUND Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) is a noninvasive uterine-preserving treatment alternative to hysterectomy for women with symptomatic uterine leiomyomas (fibroids). Uterine fibroids commonly occur, have a broad impact on women's health and lifestyle, continue to be the main indication for hysterectomy, and represent a costly public health burden. ...

Failure to become and remain pregnant after IVF depends on multiple factors including but not limited to the ability of the uterus to implant embryo and to carry a pregnancy to term. One of the factors which adversely affect fertility is the presence of uterine fibroids [1]. The closer the fibroids are to the uterine cavity, the greater their effect is on female fertility [2]. Reproduction is a...

Uterine fibroids are considered to be the most frequently occurring tumours in females. The majority of fibroids do not require any treatment. When symptomatic, the major ailments include abnormal uterine bleeding, painful menstruation, pelvic pressure or pain, urinary problems, constipation, infertility, and recurrent pregnancy loss. Surgery remains a mainstay of symptomatic uterine fibroids t...

OBJECTIVES This report seeks to introduce some cases of the patients who received magnetic resonance imaging (MRI)-guided high intensity focused ultrasound (HIFU) surgery (MRgFUS)-based intramural uterine fibroids treatment where the post-MRgFUS intramural uterine fibroids decreased in its volume and protruded towards the endometrial cavity to be expelled by hysteroscopy. METHODS Of the 157 p...

This 45-year-old woman was a tertiary referral to our Myoma Service with a diagnosis of symptomatic fibroids confirmed by ultrasound and MRI. Clinically, the uterine mass was equivalent to 28–30 weeks gestation. In view of her age and massive fibroids with menorrhagia, she had previously been offered a hysterectomy but wished to preserve fertility potential and requested a myomectomy. Her preop...

Background/introduction With regards to MR-HIFU ablation of uterine fibroids, there have been no screening MR criteria that comprehensively consider multiple influencing factors. The aims of this study was to generate screening MRI-based prediction model for therapeutic responses of MR-guided high-intensity focused ultrasound (MR-HIFU) ablation of uterine fibroids comprehensively considering mu...

Uterine fibroids are the most common benign uterine tumours. Clinical symptoms include abnormal bleeding, pelvic pressure, pelvic pain, infertility and obstetric complications. Approximately one third of women with fibroids will require treatment. The management also depends on the number, size, and location of the fibroids. There are surgical and non-surgical treatment options. The choice of t...

OBJECTIVE To estimate the cost-effectiveness of a treatment strategy for symptomatic uterine fibroids, which starts with Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) as compared with current practice comprising uterine artery embolisation, myomectomy and hysterectomy. DESIGN Cost-utility analysis based on a Markov model. SETTING National Health Service (NHS) Trusts in Engla...

OBJECTIVES To explore the atherogenic hypothesis of uterine fibroids among Chinese women. METHODS In a case-control study, 335 patients confirmed by ultrasound or hysterectomy surgery and 539 controls were enrolled between October 1, 2009 and April 1, 2012. Unconditional logistic regressions were used to calculate the odds ratios (ORs) for the associations of subclinical atherogenic and cardi...