We evaluated the prevalence of autoimmune thyroiditis in a random sample of 1188 schoolchildren aged 8-13 years with normalized iodine intake in the Islamic Republic of Iran. The prevalence of goitre was 39.6%; the majority had palpable but non-visible goitre. Of a subsample of 500 children, median urinary iodine excretion (18/8 microg/dL) indicated normal iodine intake. Thyroid peroxidase (TPO...

To decrease total body iodine is a key point in preparation for radioiodine study and therapy. We introduced a stringent self-managed low iodine diet (LID) and compared the outcome to that of the conventional restricted iodine diet (RID) for outpatients. We measured urine iodine to creatinine ratios (I/Cr) in patients prepared with RID for one week, LID for one week, or LID for two weeks. Mean ...

Iodine is essential for normal development, and its deficiency can cause growth retardation and irreversible brain damage. Nowadays, the main source of iodine is iodised salt. However, in many countries discretional use of salt (cooking and table salt) is increasingly being replaced by salt from processed foods. This situation has raised concern about the risk of iodine inadequacy if the food i...

Objective: Universal salt iodization is an effective strategy to optimize population-level iodine. At the same time as salt-lowering initiatives are encouraged globally, there is concern about compromised iodine intakes. This study investigated whether salt intakes at recommended levels resulted in a suboptimal iodine status in a country where salt is the vehicle for iodine fortification. Metho...

Background: Iodine is required throughout pregnancy for thyroid hormone production, which is essential for fetal brain development. Studies of iodine status in pregnant women from the United Kingdom (UK) have focused on early gestation (,16 wk). Data on the effect of advancing gestation on urinary iodine excretion are conflicting, with suggestions of both an increase and a

source of faecal iodine is endogenous thyroid hormone, a fraction of which is excreted into the bile (Myant, 1956). Further evidence for an endogenous origin of faecal iodine is obtained from balance studies in patients with abnormal thyroid function (Harrison et al., 1965a). Patients with thyrotoxicosis excrete significantly more iodine in the faeces than normal, ranging from 21 to 72 ,tg/ day...

INTRODUCTION Iodine deficiency disorder (IDD) is one of the preventable major public health problems in India. It has been always thought that goitre was only found in the Himalayan goitre belt. Recent surveys outside the conventional goitre belt have identified foci of iodine deficiency in other parts of India. AIM 1) To assess the prevalence of goitre among school-going children in the age ...

The two traditional methods for the assessment of iodine deficiency in a given area are the estimation of urinary excretion of iodine, and the prevalence of goiter. In field studies, the estimation of urinary iodine excretion (UIE) in random urine specimens provides an adequate assessment of a population's iodine nutrition. The recommended method is the classic one, based on Sandell-Kolthoff re...