Paragangliomas (PGLs) are rare neuroendocrine neoplasms of the autonomic nervous system dispersed from the skull base to the pelvic floor. We reported an extremely rare case with coexisting PGL of the retroperitoneum and urinary bladder. The patient complained of episodes of severe headache and palpitation during micturition, with a 1-year history of uncontrolled hypertension. The (131)I-metaio...

Urinary tract cancers are common and comprise a gamut of lesions ranging from small benign tumors to aggressive neoplasms with high mortality. The predominant urinary tract malignancy is bladder cancer. The clinical challenge is early detection and adequate follow-up because recurrence is high and delayed diagnosis is associated with poor prognosis. Primary care physicians form a key part of th...

OBJECTIVES The aims of this study are to highlight the clinicopathological features of urinary bladder cancer in Yemen, and to describe the histological grading of urothelial neoplasms according to the World Health Organization and International Society of Urologic pathology (WHO/ISUP 1998) classification. METHODS This is a descriptive record-based study of 316 cases of bladder cancer diagnos...

Primary bladder tumor is a frequent urological malignancy, whereas the incidence of secondary bladder tumor from a distant organ is quite rare. Secondary bladder neoplasms represent no more than 3% of all malignant bladder tumors in surgical specimens, of which distant metastases from stomach account for about 4%. The signs of bladder neoplasm in a patient with malignancy elsewhere should alarm...

Industrial urinary bladder cancer in dye workers has been shown to be caused by exposure to certain aromatic amines (cf. 21 for review). Animal experiments have indicated that it is likely that the carcinogens are o-aminophenol metabolites (4, 5) and that these metabolites probably are carried to the urinary bladder by the urine (26, 41). Unidentified diazotizable aromatic amines in the urine o...

abstract: urinary bladder hemangiomas are very rare and accounting for 0.6% of all urinry bladder toumors. it is rare cause of hematuria. a 8-year old boy presented with painless gross hematuria for one week. he had past history of this problem 5 months ago. physical examination revealed no unusual findings. sonogeraphy and ct scan showed intraluminal bladder mass with exteravesical cyctic comp...

The ability of urothelial tumors of the urinary bladder to metastasize via the lymphatic circulation and the extent of metastatic involvement of regional lymph nodes is an important parameter in the staging and prognosis of these neoplasms. Accordingly, we examined the site and morphology of initial lymphatic vessels in the mucosa of the human urinary bladder in patients with invasive transitio...

Background. Bladder cancer is a serious problem of modern oncourology due to the annual increase in number diagnosed malignant neoplasms urinary system. High-risk muscle-invasive and non-muscle-invasive forms are subject surgical treatment, while open radical cystectomy serves as “gold standard”. Laparoscopic robot-assisted competitors this method. To date, robotic method removing bladder least...

INTRODUCTION Recently, expression of the UHRF1 gene was found to be up-regulated in numerous neoplasms, including the urinary bladder transitional cell carcinoma (TCC). OBJECTIVE The aim of our study was to determine if the expression levels of UHRF1 gene correlates with the major pathological characteristics of the tumor and patients' clinical outcome. MATERIALS AND METHODS In our study, w...

INTRODUCTION Large cell neuroendocrine carcinoma (LCNC) is defined in the urinary bladder, as in other sites, as a high-grade neoplasm exhibiting neuroendocrine features at the H&E level, high mitotic activity and evidence of neuroendocrine differentiation by immunohistochemistry. We report a case of pure bladder LCNC with review of the literature. METHODS A 68-year-old male presented with gr...