BACKGROUND Matrix Metalloproteinases (MMPs) are key molecules for tumor growth, invasion and metastasis. Over-expression of different MMPs in tumor tissues can disturb the homeostasis and increase the level of various body fluids. Many MMPs including high molecular weights (HMWs) were detected in the urine of prostate and bladder cancer patients. Our aim here is to assess the usefulness of HMW ...

Schistosomiasis (bilharziasis) is one of the most widespread parasitoses in the world (about 300 million affected people). The central nervous system may be involved. We were unable to find a published description of the computed tomographic (CT) appearance of intracerebral schistosomiasis. This article reports a case. CT disclosed a large infiltrating mass lesion that mimicked a glioblastoma. ...

Schistosomiasis also known as Bilharziasis, is a parasitic disease that dates back to antiquity. The ancient Egyptians, through settling and cultivating the Nile valley, were among the first to contract the disease. Thus, the main symptom hematuria was mentioned in Egyptian papyri (1500-1800 B.C.), and schistosome eggs were identified in Egyptian mummies through paleopathologic studies. In 1852...

Of the various pathological causes of pulmonary endarteritis and right heart failure, schistosomiasis is probably the least familiar outside Egypt and other countries where the disease is endemic. It has long been known that bilharzia ova are sometimes deposited in the lungs (Belleli, 1885; Turner, 1909), and that adult worms of S. haematobium, often coupled males and females, may be found in t...

Objectives: Manufacturing and spraying workers of organophosphate pesticides (OPs) could suffer from testicular spermogenesis and steroidogesis dysfunctions particularly when their degradation is subnormal. Aim: Exploration of spermatogenic and endocrinologic testicular functions and paraoxonase/arylesterase (PON1/ARY) degrading activities of the organophosphate parathion and its oxon in their ...

OBJECTIVE The Fas-Fas ligand (FasL) system has been recognized as a major pathway for the induction of apoptosis in cells and tissues. Fas-mediated apoptosis is deeply involved in cancer cell death brought about by the immune system. This study was performed to determine the Fas and FasL expression in human bladder cancer and the impact of schistosomiasis infection. MATERIAL AND METHODS Of th...

BACKGROUND The morbid effects of urinary bilharziasis are becoming more evident with the advent of sophisticated diagnostics such as ultrasound. However, such diagnosis of Schistosoma haematobium morbidity is often hampered by lack of funds, proper equipment, or training. OBJECTIVE We performed a cross-sectional investigation of schoolchildren in a highly endemic area of east central Zimbabwe...