RELATED LINKS Imagine that a killer is on the loose, one who shoots his victims and flees. Police investigators would undoubtedly respond by visiting each crime scene and meticulously searching for clues. They would photograph the body, take fingerprints and question witnesses. An autopsy would recover the bullet for tests. The authorities could then use this information to establish exactly wh...

To have one’s hunches about how a simple combination of processes will behave repeated dashed by one’s own computer program is a humbling experience that no experimental psychologist should miss. Surprises are likely when the model has properties that are inherently difficult to understand, such as variability, parallelism, and nonlinearity—all, undoubtedly, properties of the brain. Hintzman, 1990

The recent bus crash in Switzerland involving many children provides several lessons for the pre-hospital care community. The use of multiple helicopters that are capable of flying at night and that carry advanced medical pre-hospital teams undoubtedly saved lives following the tragedy. We describe the medical response to the incident and the lessons that can be learned for emergency medical se...

Undoubtedly, the capacity of both second and third generation cellular networks is limited by mutual interferences between transmitting network elements. Regardless of the access scheme, one user’s transmitted signal ultimately represents interference for other users, and consequently degrades system performance. Minimizing radiated power is hence beneficial not only from the viewpoint of reduc...

Plasmodium falciparum, the protozoan parasite causing falciparum malaria, is undoubtedly highly versatile when it comes to survival and defence strategies. Strategies adopted by the asexual blood stages of Plasmodium range from unique pathways of nutrient uptake to immune evasion strategies and multiple drug resistance. Studying the survival strategies of Plasmodium could help us envisage strat...

1,4 dihydropyridines (e.g. nifedipine) undoubtedly are among the most powerful calcium antagonists. They act by blocking Ca channels when bound from the outside of the sarcolemma on a proteinic receptor (Glossmann et al. 1982). From inotropic measurements it had been supposed that a new dihydropyridine compound (BAY-K 8644, Methyl

My patients have appreciated receiving minimally invasive cosmetic enhancement without anesthesia, drilling, or more expensive restorations. Because caries infiltration prevents lesion progression, it prolongs the life of the tooth and provides a "simple" solution for patients who are known for poor compliance. Undoubtedly, this innovative material and technique will help many patients avoid ma...

Monoclonal antibodies that target immune checkpoints are undoubtedly changing the therapeutic landscape of different human malignancies. Here we comment on the effects of blocking cytotoxic T lymphocyte-associated protein 4 (CTLA4) by means of the monoclonal antibody tremelimumab in patients with refractory malignant mesothelioma, a deadly disease with no effective therapeutic options.

A micro dissection of the pachytene threads of Tradescantia virginica L. shows that the relation of the chromosomes is a matter of continuous linkage in a chain and that, undoubtedly, division and segregation are everywhere processes of abstriction with subsequent mechanical distribution of the elements.

Since its recent implementation at one of the world's largest high-throughput sequencing centers, the utility of MP-RCA for DNA sequencing has been thoroughly validated. However, applications of this technology extend far beyond DNA sequencing. While many of these applications have been explored in this chapter, the future will undoubtedly add to this growing list.