abstractbackground: fetal bovine serum (fbs) is widely used in cell culture laboratories,risk of zoonotic infections and allergic side effects create obstacles for its use inclinical trials. therefore, an alternative supplement with proper inherent growthpromotingactivities is demanded.objective: to find fbs substitute, we tested human umbilical cord blood serum(hucs) for proliferation of human...

stem cells are naïve or master cells. this means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. stem cells are found in many parts of the human body, although some sources have richer concentrations than others. some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and hu...

There have been various forms of mesenchymal stem cell-like (MSC-like) cells isolated from umbilical cords (UCs). The isolation of umbilical cord lining stem cells (ULSCs) may be of great value for those interested in a possible treatment to several disease/disorders. Unlike umbilical cord blood cells, these cells are unique because they can be expanded to therapeutically relevant numbers and c...

background: umbilical cord blood (ucb) is an alternative source of hematopoietic stem cell transplantation (hsct), used in leukemia treatment. cd26+ cells, a fraction of cd34 positive cells, are a major population of ucb cells which negatively regulate the in vivo homing and engraftment of hscs. cd26 is highly expressed in various cells such as hscs, immune cells, fibroblasts, and epithelial ce...

human umbilical cord matrix (hucm) is considered as a promising source of mesenchymal stem cells (mscs) due to several advantages over other tissues. the potential of neural differentiation of hucm-mscs is of great interest in the context of treating neurodegenerative diseases. in recent years, considerable efforts have been made to establish in vitro conditions for improving the differentiatio...

Umbilical cord nonseverance (UCNS) is the practice of leaving umbilical attached to placenta after delivery. Limited case reports exist revealing adverse outcomes UCNS. We report a neonatal omphalitis associated with Escherichia coli bacteremia and urinary tract infection

Introduction and Objectives: Annually one million newborns die due to the umbilical cord infection. Thus, in this study, we aimed toevaluate the effect of topical aloe vera gel on umbilical cord complications. Methods: This randomized clinical trial was performed in maternity ward of Ghaem Hospital, Mashhad, Iran The samples were selected through convenience sampling and were randomly divided i...

Tumors of the umbilical cord are rare anomalies and should be considered when using prenatal ultrasound for detection of cystic lesions. Differential diagnosis of umbilical cord tumors should comprise umbilical cord teratoma, hemangioma and angiomyxoma. It can also be an umbilical cord polyp, umbilical cord cyst, hernia into the cord and omphalocele, which are mostly isolated findings, except o...

Background: The appropriate moment for clamping the umbilical cord is controversial. Immediate cord clamping (ICC) is an item of active management of the third stage of labor (AMTSL). Unclamped umbilical cord may cause inconvenience in preterm neonates because they commonly need some levels of emergent services. Some studies revealed delayed cord clamping (DCC) of preterm neonates results in be...

Abstract: Umbilical cord prolapse is an uncommon obstetric emergency with high neonatal morbidity and mortality. It a rare entity incidence ranging from 0.1 to 0.6%. Timely recognition immediate interventions are needed for better outcome. Here, we present case of 28-year-old multigravida term pregnancy seven hours following rupture mem...