BACKGROUND Tree nut allergy is one of the common potentially life-threatening food allergies in children and adults. Recombinant food allergens offer new perspectives to solve problems of clinical and molecular allergology in diagnosis, research, and therapy of food allergies. So far, superoxide dismutase (s) has been identified as a panallergen and studied in different allergenic sources. Mang...

The common pistachio psylla Agonoscena pistaciae is a key pest of pistachio in Iran. A study was conducted to determine the spatial distribution of psylla nymphs and eggs in a 10 ha pistachio orchard in the Rafsanjan region, southeast of Iran. Three rows, each containing 33 trees (totally 99 trees), were randomly selected in the orchard based on a stratified sampling scheme. In each of the sele...

BACKGROUND & AIMS We tested the hypothesis that oral administration of bile salts, which are known to increase the biliary excretion of unconjugated bilirubin (UCB), decreases unconjugated hyperbilirubinemia in the Gunn rat model. METHODS Adult Gunn rats were fed a standard diet or the same diet supplemented with 0.5 weight % ursodeoxycholic acid (UDCA) or cholic acid (CA) for 1 or 6 weeks. U...

Human mesenchymal stromal cells (MSC) have been shown to support the growth and differentiation of hematopoietic stem cells (HSC). We hypothesized that intra-osseous (IO) co-transplantation of MSC and umbilical cord blood (UCB) may be effective in improving early HSC engraftment, as IO transplantation has been demonstrated to enhance UCB engraftment in NOD SCID-gamma (NSG) mice. Following non-l...

1 Principal Investigator of Horticulture and Curator, USDA Naitonal Clonal Germplasm Repository for Asimina species, Atwood Research Facility, Kentucky State University, Frankfort, KY 40601-2355. To whom reprint requests should be addressed. 2 Co-Investigator of Horticulture, Atwood Research Facility, Kentucky State University, Frankfort, KY 40601-2355 Abstract The pawpaw [Asimina triloba (L.) ...

BACKGROUND AND AIMS The primary physiological mechanism influencing tree vigour in size-controlling rootstocks of peach has been related to the hydraulic conductance of the rootstock. Differences in rootstock hydraulic conductance are a function of rootstock xylem vessel characteristics. The present research examined whether the vigour and xylem vessel characteristics of the rootstock influence...

In vitro and in vivo studies have demonstrated that UCB (unconjugated bilirubin) is neurotoxic. Although previous studies suggested that both MRP1 (multidrug resistance-associated protein 1) and MDR1 (multidrug resistance protein 1) may protect cells against accumulation of UCB, direct comparison of their role in UCB transport was never performed. To this end, we used an inducible siRNA (small ...

The transport of highly purified 3H-labelled unconjugated bilirubin (UCB) was investigated in rat liver plasma membrane vesicles enriched in the canalicular domain and found to be stimulated (more than 5-fold) by the addition of ATP. Other nucleotides, such as AMP, ADP, GTP and a non-hydrolysable ATP analogue (adenosine 5'-[alpha, beta-methylene] triphosphate), did not stimulate [3H]UCB transpo...

ABSTRACT Alternaria isolates were obtained from various pistachio tissues collected in five orchards in California. For all isolates, morphological characteristics of the colony and sporulation apparatus were determined and compared with those of representative isolates of A. alternata, A. tenuissima, A. arborescens, and A. infectoria. A selection of the pistachio isolates and the representativ...

The cellular and molecular mechanisms underlying the blunted allo-responsiveness of umbilical cord blood (UCB) T cells have not been fully elucidated. Protein expression of NFATc2 (nuclear factor of activated T cells c2), a critical transcription factor necessary for up-regulation of multiple cytokines known to amplify Tcell allogeneic responses, is reduced in UCB T cells. Affymetrix oligonucle...