AIMS To define the prevalence of dyslipidaemia in young diabetic patients in Peninsular Malaysia and the contributory factors of dyslipidaemia in these subjects. METHODS This is a cross-sectional study involving 848 young diabetic patients from seven different centres, with representation from the three main ethnic groups. Clinical history and physical examination was done and blood taken for...

BACKGROUND Although much attention has been focused on the association between chronic hyperglycemia and cerebrovascular diseases in type 2 diabetes mellitus (DM) patients, there is no data regarding the risk of ischemic stroke after a hyperosmolar hyperglycemic state (HHS) attack. The objective of this study was to investigate the risk of ischemic stroke in type 2 DM patients after an HHS atta...

objective: type 2 diabetes mellitus (dm-2) is a chronic and progressive metabolic disorder known as a serious threatening condition in the individual and society. type 2 diabetes mellitus is known as the major cause of cardiovascular diseases (cvd). contradictory evidences about the effect of omega-3 fatty acids on cvd risk factors, particularly hypertension. the aim of this study was to determ...

From 2008 through 2015, a total of 9,092 incident cases of diabetes mellitus (DM) were reported among active component service members (incidence rate 82.8 cases per 100,000 person-years [p-yrs]). The overall incidence rate of type 1 DM was 3.0 cases per 100,000 p-yrs. The rate of type 2 DM was 74.5 cases per 100,000 p-yrs and rates doubled within each successive age group. Male service members...

The aim of our study was to evaluate antibodies against thyroglobulin (anti-TG) and thyroid peroxidase (anti-TPO) - markers of autoimmune thyroiditis - in several groups of adult patients with type 1 and type 2 diabetes mellitus (DM). We were particularly interested whether the presence of thyroid antibodies is related to the positivity of glutamic acid decarboxylase antibodies (anti-GAD). We f...

Dysregulation of the Na/K-ATPase (NKA) in the kidney, cardiovascular system, and peripheral nervous system is believed to contribute to pathogenesis of diabetes mellitus (DM) and its complications. Recently we demonstrated that, in addition to endogenous ouabain (EO), mammalian tissues contain another NKA inhibitor, a bufadienolide marinobufagenin (MBG). In vitro MBG, a natriuretic and a vasoco...

BACKGROUND Gastrointestinal (GI) tract symptoms are common among patients with diabetes mellitus (DM) seen in tertiary care centers. The degree to which this reflects referral bias is unclear. OBJECTIVES To determine whether GI tract symptoms are more prevalent in unselected patients with DM from the general community compared with their age- and sex-matched counterparts without DM and to ass...

CONTEXT Kidney disease in type 2 diabetes mellitus (DM) is more heterogeneous than in type 1 DM. Reduced glomerular filtration rate (GFR) among individuals with type 2 DM may not always be due to classic diabetic glomerulosclerosis, which is associated with albuminuria and retinopathy. OBJECTIVE To determine the prevalence of chronic renal insufficiency (CRI), defined as a GFR less than 60 mL...

BACKGROUND Diabetes mellitus type 2 (DM) is known to be a major risk factor for the development of active tuberculosis, although its influence on latent Mycobacterium tuberculosis infection (hereafter, "latent infection") remains poorly characterized. METHODS We examined circulating plasma cytokine levels in individuals with latent infection with DM or pre-DM (ie, intermediate hyperglycemia) ...

OBJECTIVE To classify individuals with diabetes mellitus (DM) into DM subtypes using population-based studies. DESIGN Population-based survey. SETTING Individuals participated in 2003-2004, 2005-2006, or 2009-2010 the National Health and Nutrition Examination Survey (NHANES), and 2010 Coronary Artery Risk Development in Young Adults (CARDIA) survey (research materials obtained from the Nati...