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The purpose of this study is to assess the safety and efficacy finerenone therapy in type 2 diabetes mellitus (T2DM) patients with cardiovascular chronic renal diseases. This meta-analysis assesses treatment diabetic kidney disease (DKD). A comprehensive search PubMed, Embase, Google Scholar databases was performed identify relevant randomized controlled trials (RCTs). To quantify effects finer...
Potato spindle tuber viroid (PSTVd) is one of the smallest (about 360 nt) infectious plant agents. It is composed of a single-stranded circular non-coding RNA molecule. In the course of previous passage experiments with two intermediate PSTVd variants I2 and I4, three non-infectious clones (I2-50, I4-37 and I4 VI-17) were found. When inoculated separately as cDNAs on tomato "Rutgers" test plant...
OBJECTIVE To compare important clinical outcomes between early and delayed initiation of antiretroviral therapy (ART) in adults who had a co-infection of human immunodeficiency virus (HIV) and tuberculosis (TB). METHODS We performed a systematic search for relevant publications on PubMed, EMBASE, and the International Clinical Trials Registry Platform. We included randomized controlled trials...
BACKGROUND Given the controversy around mode of delivery, our objective was to assess the evidence regarding the safest mode of delivery for actively resuscitated extremely preterm cephalic/non-cephalic twin pairs before 28 weeks of gestation. METHODS We searched Cochrane CENTRAL, MEDLINE, EMBASE and http://clinicaltrials.gov from January 1994 to January 2017. Two reviewers independently scr...
Diffusible iodine-based contrast-enhanced computed tomography presents a comparatively new tool kit for imaging fine-scale three-dimensional phenotypes that is rapidly becoming standard anatomical practice. However, relatively few studies have attempted to look at subtle differences in staining protocols or attempted to model tissue reactions to gain insight into staining mechanisms. Here, two ...
BACKGROUND Killed whole-cell oral cholera vaccines (kOCVs) are becoming a standard cholera control and prevention tool. However, vaccine efficacy and direct effectiveness estimates have varied, with differences in study design, location, follow-up duration, and vaccine composition posing challenges for public health decision making. We did a systematic review and meta-analysis to generate avera...
In order to determine the effects of number of irrigations on stages of development, yield, and yield components of cumin, an experiment was conducted in 1993 - 94 growing season with a randomized complete block design and four replications. The location of the experiment was Isfahan University of Technology Research Station in Shervedan Field. The irrigation treatments were: I1- Irrigation aft...
A model of iodine chemistry in the marine boundary layer (MBL) has been used to investigate the impact of daytime coastal emissions of molecular iodine (I2). The model contains a full treatment of gas-phase iodine chemistry, combined with a description of the nucleation and growth, by condensation and coagulation, of iodine oxide nano-particles. In-situ measurements of coastal emissions of I2 m...
We report the 790 nm photofragmentation of mass-selected I2 2 •Arn clusters, n51 to 27. We determine the I1I caging efficiency as a function of the number of solvent Ar atoms and compare these results with I2 2 in CO2 clusters. Caging is much less effective with Ar. In addition to ‘‘normal’’ caged photoproducts ~I2 2 •Arm , where m,n!, the evaporation process following photoexcitation produces ...
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