We incorporated anti-Parkinsonian drug, levodopa (dopa), in Zn/Al-LDH by coprecipitation method to form dopa-LDH nanocomposite. Further coating of Tween-80 on the external surfaces of dopa-LDH nanocomposite was achieved through the oxygen of C=O group of Tween-80 with the layer of dopa-LDH nanocomposite. The final product is called Tween-dopa-LDH nanocomposite. The X-ray diffraction indicates t...

Sea buckthorn oil (SBO) contains fatty acids that have an anti-aging effect. The delivery system ofSBO can be improved by a nanoemulsion system. purpose of this study was to determine thephysical stability SBO (NSB) with Tween 80 variation. NSB made 1% SBOand variation 35% (FI); 40% (FII) and 45% (FIII). stored in climatic chamberat 30 ± 2°C RH 65%±5% for 90 days. Samples were taken before stor...

Self-emulsifying compositions are the basis of oral drug delivery systems used to improve solubility and increase bioavailability active pharmaceutical ingredients that poorly soluble in aqueous medium gastric juice. Aim. To develop self-emulsifying using simvastatin as an ingredient. Materials methods. During development composition mixture, excipients, such solvents, co-solvents, surfactants ...

Micro-emulsions are of great importance in food industry since they are used in various food applications. In the present study edible olive oil w/o microemulsions without the addition of a co-surfactant were studied. Both chemical and natural surfactants were examined. The chemical surfactants used were Tween 20, 40, 80 and Span 20, 80. The natural substances used as surfactants were endogenou...

Bile of the rat and of other species stimulates the uptake of @-carotene from a micellar solution of Tween 40 (polyoxyethylene anhydrosorbitol monopalmitate) and its cleavage into retinol ester by intestinal sections of the rat incubated in vitro. Sodium glycocholate and several other conjugated bile acids substitute completely for bile. Glycocholate also stimulates @-carotene cleavage by intes...

An isolated Fusarium anthophilum (A. Braun) Wollenweber (isolate 16C) has been considered as a candidate for microbial control of barnyard grass [Echinochloa crus-galli (L.) P. Beauv]. The effects of nutrition on conidiation, germination rate and germ-tube elongation of conidia of the fungus were evaluated. Conidia yield, conidial germination and conidial germ-tube elongation of the fungus grow...

in this study formation and properties of o/w emulsion stabilized by a mixture of sodium caseinate (2, 5 and 10 wt %) and non-ionic emulsifier tween 80, sorbitan mono-9-octadecenoate, (0, 0.5, 1 and 1.5 wt %) were investigated at various ph values(3, 5 and 7) and calcium ion concentrations (0, 0.2, 0.4 and 0.6 wt%). emulsion samples were prepared by using a sonicator with a nominal power output...

objective(s):  the aim of this study was to prepare a nanosuspension formulation as a new vehicle for the improvement of the ocular delivery of vitamin a.  material and methods:   formulations were designed based on full factorial design. a high pressure homogenization technique was used to produce nanosuspensions. fifteen formulations were prepared by the use of different combinations of surfa...

The goal of the present study was to investigate the feasibility of using non-ionic surfactant vesicles as carriers for the sustained delivery of water soluble anti-cancer drug Capecitabine, used in the treatment of colorectal cancer. The niosomal formulations were prepared using various non-ionic surfactants (span 40, span 60, tween 40 and tween 60) in the presence of cholesterol, by thin film...