نتایج جستجو برای: tumor necrosis factor alpha tnf α
تعداد نتایج: 1490844 فیلتر نتایج به سال:
Mastitis is one of the most prevalent and costly diseases affecting dairy cattle production. In the present study, effects of tumor necrosis factor (alpha isomer) gene (TNF-α) polymorphisms on milk somatic cell count (SCS) and subclinical mastitis was investigated in 121 Holstein dairy cattle. The polymorphisms of a 303 bp fragment of TNF-α gene were investigated by PBR and PCR-SSCP techniques....
Purpose: To study the influence of etanercept on diabetic retinopathy in rats via tumor necrosis factor alpha (TNF-α)/nuclear kappa-light-chain-enhancer activated B cells (NF-κB) signaling pathway. 
 Methods: Thirty-six Sprague-Dawley (SD) were randomly divided into normal, model and groups. The expression Caspase-3 was determined by immunohistochemistry, while relative protein mRNA levels...
Objective: Cystatin C is considered an important marker for the detection of renal dysfunction. It was aimed to determine cystatin levels, status oxidant-antioxidant and inflammation in hemodialysis (HD) patients. Methods: The study groups consisted 20 HD patients healthy controls. Blood samples were obtained from control group before hemodialysis. Serum C, total antioxidant capacity (TAC), oxi...
Calcific aortic valve disease (CAVD) represents a slowly progressive pathologic process associated with major morbidity and mortality. The process is characterized by multiple steps: inflammation, fibrosis, and calcification. Numerous studies focalized on its physiopathology highlighting different "actors" for the multiple "acts." This paper focuses on the role of the tumor necrosis factor supe...
Background: Polycystic Ovarian Syndrome (PCOS) is a pro-inflammatory condition that supports the development of metabolic aberration and ovarian dysfunction. Chronic inflammation and the increased levels of androgens in this group of patients and their impact on the immune system may increase the risk of developing malignancies, including ovarian cancer. Thus, we interacted ovarian tumor cells ...
BACKGROUND Pancreatic ductal adenocarcinoma (PDAC) is one of the most common cancer death reasons. Anti-tumor necrosis factor-alpha (TNF-α) antibodies have shown promising effects in PDAC pre-clinical models. However, the prognostic values of TNF-α, underlying mechanisms by which anti-TNF-α treatments inhibit PDAC, and potential synergistic effects of anti-TNF-α treatments with chemotherapy are...
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