نتایج جستجو برای: tumor associated natural killer cells

تعداد نتایج: 3299976  

Alireza Azargoon Farhad Shahsavar Kobra Entezami Tahereh Mousavi,

Background: Natural killer (NK) cells are the effector cells of innate immunity that respond to infection and tumor. Interactions between killer cell immunoglobulin like receptors (KIR) and human leukocyte antigen (HLA) class I molecules regulate NK cells responses to eliminate infected and transformed cells. Objective: To investigate the impact of KIR genes, HLA ligand genes, and KIR-HLA combi...

Journal: :Haematologica 2016
Letizia Muccio Alice Bertaina Michela Falco Daniela Pende Raffaella Meazza Miguel Lopez-Botet Lorenzo Moretta Franco Locatelli Alessandro Moretta Mariella Della Chiesa

We analyzed the impact of human cytomegalovirus infection on the development of natural killer cells in 27 pediatric patients affected by hematological malignancies, who had received a HLA-haploidentical hematopoietic stem cell transplantation, depleted of both α/β+ T cells and B cells. In line with previous studies in adult recipients of umbilical cord blood transplantation, we found that huma...

Journal: :iranian journal of immunology 0
farhad shahsavar department of immunology, lorestan university of medical sciences, khorramabad tahereh mousavi department of immunology, tehran university of medical sciences alireza azargoon department of internal medicine, lorestan university of medical sciences, khorramabad, iran kobra entezami department of immunology, tehran university of medical sciences

background: natural killer (nk) cells are the effector cells of innate immunity that respond to infection and tumor. interactions between killer cell immunoglobulin like receptors (kir) and human leukocyte antigen (hla) class i molecules regulate nk cells responses to eliminate infected and transformed cells. objective: to investigate the impact of kir genes, hla ligand genes, and kir-hla combi...

Journal: :Advances in immunology 2014
Assaf Marcus Benjamin G Gowen Thornton W Thompson Alexandre Iannello Michele Ardolino Weiwen Deng Lin Wang Nataliya Shifrin David H Raulet

In recent years, roles of the immune system in immune surveillance of cancer have been explored using a variety of approaches. The roles of the adaptive immune system have been a major emphasis, but increasing evidence supports a role for innate immune effector cells such as natural killer (NK) cells in tumor surveillance. Here, we discuss some of the evidence for roles in tumor surveillance of...

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