The precise origin of cells infiltrating tuberculin skin reactions was studied with the technique of immunofluorescence. Thymectomized, irradiated Lewis rats were restored with bone marrow from allogeneic or F(1) donors. They were passively sensitized to tuberculin by a subsequent transfer of Lewis lymph node cells and were given intradermal skin tests with tuberculoprotein. In 24 hr reactions ...

background & objectives: annually, many muslims fast during the month of ramadan worldwide. this practice has different favorable medical and physiological effects, such as improved serum lipid profile and blood glucose level due to changes in diet and sleep patterns. it has also been hypothesized that ramadan fasting may affect the immune system. as reported, ramadan fasting can influence the ...

BACKGROUND The annual risk of Tuberculosis infection (ARTI) is a key indicator in epidemiology, of the extent of transmission in a community. There have been several suggested methods in order to evaluate the prevalence of Tuberculosis infection using tuberculin skin data. This survey estimates the ARTI in young Hellenic air force recruits. The effect of BCG vaccination has also been investigat...

CONTEXT Concern about transmission of Mycobacterium tuberculosis on college campuses has prompted some schools to institute tuberculin skin test screening of students, but this screening has never been evaluated. OBJECTIVE To describe tuberculin skin test screening practices and results of screening in colleges and universities in the United States. DESIGN AND SETTING Self-administered mail...

background according to several studies, diabetes mellitus has been recognized as one of the main risk factors for pulmonary tuberculosis (ptb). objectives the main purpose of this study was to determine the frequency of smear-positive pulmonary tuberculosis (tb) in patients with diabetes. materials and methods this cross-sectional study was conducted from april 2010 to december 2011 in ali asg...

OBJECTIVE Between November 1994 and April 1995, more than 3300 students in 49 schools in two counties in New York were potentially exposed to five school bus drivers with tuberculosis. This investigation was carried out to determine the extent of transmission of Mycobacterium tuberculosis among students. METHODS Components of the epidemiologic investigation included tuberculin skin-test scree...

To evaluate the effect of BCG vaccination and T lymphocyte subpopulations on the reactivity to the tuberculin skin test, 113 asymptomatic HIV+ individuals were tuberculin tested by intradermal injection of 5TU of purified protein derivative and the levels of circulating lymphocyte (CD3, CD4 and CD8) subpopulations determined by indirect immunofluorescence. Ninety-two percent of the subjects inc...

The Enzyme Linked ImmunoSpot (ELISPOT) is a new rapid T cell based blood test (otherwise known as an interferon-c assay) for the diagnosis of latent tuberculosis infection. The commercially available form of the assay, T-SPOTH TB (Oxford Immunotec, Abingdon, UK) has European regulatory approval as an in vitro diagnostic test and is increasingly being used in clinical practice. The test is based...