LANDI, S. (University of Toronto, Toronto, Ontario, Canada), AND H. R. HELD. Physicochemical and biological studies on various preparations of tuberculin purified protein derivative. Appl. Microbiol. 13:132-139. 1965.-Tuberculin purified protein derivative (PPD) has been prepared by seven different precipitation methods from culture filtrate of Mycobacterium tuberculosis var. hominis. It was fo...

It is well known that after Bacille Calmette-Gue'rin (B.C.G.) vaccination the degree of allergy as shown by the tuberculin test is of a lesser order than that after infection with virulent tubercle bacilli. For this reason it may be necessary to perform several successively stronger tuberculin tests up to 100 units of old tuberculin (Mantoux 1/100) before a positive post-vaccination test is obt...

Ireland currently obtains its avian and bovine tuberculin purified protein derivatives (PPDs) from a single source. Because problems of supply or quality cannot be discounted, it is prudent that Ireland identify alternative supplier(s) as part of a broad risk management strategy. Therefore, the aim of this study was to compare the performance of a number of different tuberculin combinations (th...

DESCRIPTION Tuberculin Purified Protein Derivative (Mantoux) TUBERSOL for intradermal (Mantoux) tuberculin testing is available in a stabilized solution bio-equivalent to 5 U.S. units (TU) PPD-S per test dose (0.1 mL). TUBERSOL is prepared by Aventis Pasteur Limited from a large Master Batch, Connaught Tuberculin (CT68) and is a cell-free purified protein fraction obtained from a human strain o...