A touching triangle graph (TTG) representation of a planar graph is a planar drawing Γ of the graph, where each vertex is represented as a triangle and each edge e is represented as a side contact of the triangles that correspond to the end vertices of e. We call Γ a proper TTG representation if Γ determines a tiling of a triangle, where each tile corresponds to a distinct vertex of the input g...

BACKGROUND There is lack of data on prevalence of celiac disease (CD) in children with type 1 diabetes (T1D) in Arabs in the Middle East. The present investigation aims to study the prevalence rate and clinical characteristics of CD among Saudi children with T1D using a combination of the most sensitive and specific screening serologic tests (anti- tissue transglutaminase antibodies IgA [anti-T...

BACKGROUND Recent guidelines have proposed that there is a correlation between tissue transglutaminase (tTG) antibody titers and degrees of duodenal biopsy, and that duodenal biopsy can be omitted in some patients with high levels of tTG antibody. Using data of registered patients in a gastrointestinal clinic we aimed to assess the correlation between tissue transglutaminase antibody with duode...

A potential link between tissue-type transglutaminase (tTG) and cardiac hypertrophy was suggested recently. However, whether tTG is implicated in hypertrophic agonist-induced cardiac hypertrophy is not yet known. The purpose of this study was to investigate the effects of tTG on cardiomyocyte hypertrophy induced by endothelin (ET) 1. Real-time quantitative RT-PCR and Western blot analysis demon...

OBJECTIVES The aim of the present study was to evaluate diagnostic performance and actual costs in clinical practice of immumoglobulin (Ig)G/IgA deamidated gliadin peptide antibodies (DGP) as a complement to IgA antibodies against tissue transglutaminase (tTG) for the diagnosis of pediatric celiac disease (CD). METHODS All of the consecutive patients younger than 18 years tested for tTG and/o...

Sviluppo di immunosensori amperometrici e piezoeletrici per la rivelazione di anticorpi anti-tTG nella diagnosi della malattia celiaca Il presente lavoro riguarda la realizzazione di immunosensori a trasduzione amperometrica e piezoelettrica, basati sull’immobilizzazione della transglutaminasi tissutale in forma aperta (Open-tTG). Entrambe le strategie hanno permesso di ottenere un modello affi...

Tweet Timeline Generation (TTG) task aims to generate a timeline of relevant but novel tweets that summarizes the development of a given topic. A typical TTG system first retrieves tweets then detects novel tweets among them to form a timeline. In this paper, we examine the dependency of TTG on retrieval quality, and its effect on having biased evaluation. Our study showed a considerable depend...

The aim of this study was to investigate the role of tissue transglutaminase (tTG) in the pathogenesis of diabetic cardiomyopathy (DCM) and the intervention effect of rutin. DCM was induced in rats by the injection of streptozotocin (STZ; 25 mg/kg). After a preliminary examination, the rats were randomly divided into four groups: Control (n=8), STZ-induced DCM (n=8), STZ + positive drug (captop...

AIMS To investigate celiac disease (CD) and related co-morbidity in patients with familial and sporadic cardiomyopathy and in their relatives. METHODS AND RESULTS We screened anti-human-tissue-transglutaminase (IgA and IgG anti-h-tTG) and anti-endomysial antibodies (AEAs) in 238 consecutive adult patients with inherited or sporadic dilated cardiomyopathy (DCM), 418 relatives, and 2000 healthy...

Tissue transglutaminase (tTG) is a Ca(2+)-dependent enzyme which cross-links proteins via epsilon(gamma-glutamyl)lysine bridges. There is increasing evidence that tTG is involved in wound repair and tissue stabilization, as well as in physiological mechanisms leading to cell death. To investigate the role of this enzyme in tissue wounding leading to loss of Ca(2+) homoeostasis, we initially use...