Syrenomelia sequence is a rare (incidence of 1: 60000 births) [1,2] lethal pattern of congenital anomalies characterized by a number of hallmark skeletal anomalies including fusion of the lower extremities or a single lower limb, bilateral renal agenesis or dysgenesis with absent or hypoplastic renal arteries, oligohydramnios and the presence of aberrant vasculature. Prenatal sonographic detect...

BackgroundTruncus arteriosus is a congenital heart defect with high resource use, cost, and mortality. Value assessment (outcome relative to cost) can improve quality of care decrease cost. This study hypothesized that truncus repair at high-volume center would result in better outcomes lower cost (higher value) compared low-volume center.MethodsThis retrospectively analyzed multicenter cohort ...

Truncus arteriosus is characterized by the presence of a common arterial trunk arising from both ventricles while transposition of the great arteries is a cyanotic congenital heart defect that is characterized by a pulmonary artery arising from the left ventricle and an aorta arising from the right ventricle. Patients with these two conditions are usually cyanotic and are usually diagnosed with...

The cases of 23 patients whose condition was diagnosed as truncus arteriosus, type I or II, and who were seen at the Mayo Clinic during the decade preceding 1967, that is, before corrective operation became feasible, were reviewed. Ten were infants (through one year of age), and all ten have died. Eight ranged in age from more than one year through seven years of age, and all are living, except...