نتایج جستجو برای: triclosan

تعداد نتایج: 2220  

2013
John Kelly Emma Rosi-Marshall John Scott

In urban areas wastewater treatment plant (WWTP) effluent can represent a significant component of freshwater ecosystems, and WWTP effluent can be a point source for a variety of pollutants, including pharmaceuticals and personal care products (PPCPs). We analyzed two field sites in the Chicago region: (1) an urban river receiving effluent from a large WWTP; and (2) a suburban river receiving e...

Journal: :The Journal of antimicrobial chemotherapy 2009
Rabih O Darouiche Mohammad D Mansouri Purushottam V Gawande Srinivasa Madhyastha

OBJECTIVES The objectives of this study were to examine: (i) synergy of the combination of triclosan and DispersinB (DspB); (ii) in vitro efficacy and durability of triclosan + DspB-coated vascular catheters; and (iii) in vivo efficacy of triclosan + DspB-coated catheters compared with chlorhexidine-silver sulfadiazine (CH-SS)-coated and uncoated (control) vascular catheters in preventing colon...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2009
Leah M Zorrilla Emily K Gibson Susan C Jeffay Kevin M Crofton Woodrow R Setzer Ralph L Cooper Tammy E Stoker

Triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) is a potent antibacterial and antifungal compound that is widely used in personal care products, plastics, and fabrics. Recently triclosan has been shown to alter endocrine function in a variety of species. The purpose of this study was to determine effects of triclosan on pubertal development and thyroid hormone concentrations in the male rat....

2009
Mina Tabak Keren Scher Michael L. Chikindas Sima Yaron

Triclosan is a biocide whose wide use has raised a debate about the potential benefits vs. hazards of the incorporation of antimicrobials in consumer products. The purpose of the present study was to determine whether exposure of biofilms of Salmonella enterica serovar Typhimurium to triclosan influences the tolerance of the bacteria towards antibiotics such as ciprofloxacin and vice versa. A s...

2011
Alvaro Hernández Federico M. Ruiz Antonio Romero José L. Martínez

The wide utilization of biocides poses a concern on the impact of these compounds on natural bacterial populations. Furthermore, it has been demonstrated that biocides can select, at least in laboratory experiments, antibiotic resistant bacteria. This situation has raised concerns, not just on scientists and clinicians, but also on regulatory agencies, which are demanding studies on the impact ...

Journal: :Antimicrobial agents and chemotherapy 2004
Allison E Aiello Bonnie Marshall Stuart B Levy Phyllis Della-Latta Elaine Larson

The possible association between triclosan and bacterial susceptibility to antibiotic was examined among staphylococci and several species of gram-negative bacteria (GNB) isolated from the hands of individuals in a community setting. Hand cultures from individuals randomized to using either antibacterial cleaning and hygiene products (including a hand soap containing 0.2% triclosan) or nonantib...

2013
Linda Thimour-Bergström Christine Roman-Emanuel Henrik Scherstén Örjan Friberg Tomas Gudbjartsson Anders Jeppsson

OBJECTIVES The incidence of surgical site infection (SSI) after open vein harvesting in coronary artery bypass grafting (CABG) patients ranges in different studies between 2 and 20%. Triclosan is an antibacterial substance that reduces the growth of bacteria by inhibiting fatty acid synthesis. We hypothesized that wound closure with triclosan-coated sutures would reduce SSI after open vein harv...

Journal: :Canadian journal of microbiology 2006
Tuan-Nghia Phan Robert E Marquis

Triclosan was found to be a potent inhibitor of the F(H+)-ATPase of the oral pathogen Streptococcus mutans and to increase proton permeabilities of intact cells. Moreover, it acted additively with weak-acid transmembrane proton carriers, such as fluoride or sorbate, to sensitize glycolysis to acid inhibition. Even at neutral pH, triclosan could inhibit glycolysis more directly as an irreversibl...

2012
Lei Li Weimin Shen Kaiyu Zhang Xudong Tang Na Guo Fengge Shen Mingxun Xing Lihui Liua Peng Yuan Qiyun Shi Junchao Liang Lu Yu

Mycoplasmosis caused by mycoplasma has immensely reduced the performance of commercial animal husbandry, along with prevalence and increase of drug resistance in mycoplasma, thus new agents and therapies are urgently needed. Triclosan is a broad spectrum antimicrobial agent with a favorable safety profile. In the present study, we tested the antimycoplasmal activity of triclosan alone, as well ...

2011
Ojan Assadian Katrin Wehse Nils-Olaf Hübner Torsten Koburger Simone Bagel Frank Jethon Axel Kramer

BACKGROUND An in-vitro study was conducted investigating the antimicrobial efficacy of polihexanide and triclosan against clinical isolates and reference laboratory strains of Staphylococcus aureus and Escherichia coli. METHODS The minimal inhibitory concentration (MIC) and the minimal microbicidal concentration (MMC) were determined following DIN 58940-81 using a micro-dilution assay and a q...

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