drug resistance (especially multiple drug resistance) in mycobacterium tuberculosis makes global concerns in treatment and control of tuberculosis. rapid diagnosis of drug resistant strains of the bacteria has vital importance in the prognosis of the disease. the aim of this study was to identify the mutations responsible for drug resistance in mycobacterium tuberculosis strains derived from pa...

Musculoskeletal tuberculosis accounts for 1-2% of all types of tuberculosis. Tubercular abscess of the chest wall accounts for 1-5% of all cases of musculoskeletal tuberculosis. Herein, we report a case of tubercular abscess of the chest wall. The occurrence of caries rib and cold abscess of the chest wall with concomitant pulmonary tuberculosis, and tubercular lympha-denitis of neck and medias...

Background: A number of former studies have shown that tuberculosis (TB) is higher in diabetes mellitus (DM) patients than non-diabetics. Both DM and TB are major public health problems in Iran, and because of the lack of investigation in this field in the region, we conducted this study to evaluate the prevalence of DM in admitted pulmonary tuberculosis patients. Methods: The medical files of...

Throughout the first three quarters of the 20th century, the incidence of tuberculosis declined in industrialized countries (1,2) (figure 1). Part of this decline may have been due to isolation of infectious tuberculosis patients in sanitariums and the pasteurization of milk, but it is generally thought that improved housing and habitat, decreased crowding, better hygiene and sanitation, use of...

Background: The incidence of tuberculosis (TB) has increased in recent years in both developed and developing countries. Skeletal tuberculosis occurs in approximately 1% of patients with tuberculosis. The present study aimed to evaluate the epidemiology of skeletal tuberculosis in Golestan province in northeastern Iran during 2005-2014.Methods: In the present retrospective study, the epidemiolo...

BACKGROUND World Health organization (WHO) declared tuberculosis as a global emergency because it poses a serious public health threat in different countries especially, in Africa. According to WHO report of 2007, Directly Observed Treatment Short course (DOTS) coverage in Ethiopia reached 95 percent of the population; despite this fact the trend of tuberculosis in most of the districts of Ethi...

To estimate the bacterio-epidemiological situation of childhood respiratory tuberculosis in Iran, 2185 symptomatic patients of 0-14 years old were studied. Among 110 bacteriologically confirmed cases, 60% were less than five years old and the number of females was slightly more than males. In 21 % of patients, the Mantoux test was negative. None of the miliary cases had a history of BCG va...

Introduction: Extra-pulmonary tuberculosis (EPTB) arising in extra-oral region in head and neck are rare, and when swellings arise from other sites such as infraorbital region, cheek, etc, tuberculosis is not usually considered for the differential diagnosis (DD) and often the diagnosis is missed and appropriate treatment is delayed. Case Report: We report a rare entity of pri...

Tuberculosis is still one of the major global public health threats. Countries with low incidence must focus on exhausting the reservoir of future cases by preventing reactivation. Therefore, it is important to identify and effectively treat those individuals who have latent tuberculosis infection and who may develop active disease. The tuberculin skin test has been the standard for detection o...

conclusions anti-tuberculosis drugs-induced hepatotoxicity caused treatment interruption in 5.5% of the patients with tuberculosis. the majority of the patients with dih were above fifty, and 50% the cases occurred during the first two weeks after treatment onset. physicians must carefully and closely monitor such patients. background hepatotoxicity is one of the most frequent adverse events th...