Background and Aim: Traumatic brain injury is one of the leading causes of mortality and disability in young adults. Epigallocatechin-3-gallate, the antioxidant compound of green tea, has been proposed to have antioxidant and anti-inflammatory properties. This study evaluates the potential effects of epigallocatechin-3-gallate on the early clinical outcome and serum S100B levels (biomarker for ...

traumatic brain injury resulting road accidents create damage to the brain. the severe brain injury may cause extensive tissue loss of several parenchyma which results in cavities due to primary destruction and secondary injuries such as ischemia and inflammation. recent findings suggest that neuronal precursors in the adult mammalian brain can be a therapeutic target in ischemic brain injuries...

objective: to determine the effects of pre-injury consumption of anti-platelet agents on the 30-day outcomes of patients with mild traumatic brain injury (tbi). methods: this prospective cohort study was conducted at three general hospitals in tehran, iran between july 2013 and july 2014. the study population included all patients with mild tbi aged over 18 years that medicated with aspirin or ...

traumatic brain injury (tbi) is described by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. the use of human stem cells and self-assembling peptide scaffolds suggest huge potential for application in the treatment of tbi. in the present study, we surveyed the beneficial effec...

background cerebral state index (csi) is derived from electroencephalograms to monitor the level of consciousness during anesthesia. some evidence shows that this indicator has been used to detect cerebral ischemia and prognostic outcomes for traumatic brain injury (tbi). objectives the present study was designed to investigate the correlation between glasgow coma score (gcs) and csi for brain-...

objectives we aim to evaluate the role of glibenclamide on the short-term outcome of patients with dai due to moderate to severe tbi. patients and methods in this controlled randomized clinical trial, 40 patients with moderate to severe tbi were assigned to glibenclamide (n = 20) and control (n = 20) groups. six hours after admission the intervention group received 1.25 mg glibenclamide every 1...

traumatic basal ganglia hematoma is a rare condition defined as presence of hemorrhagic lesions in basal ganglia or adjacent structures suchas internal capsule, putamen and thalamus. bilateral basal ganglia hematoma are among the devastating and rare condition. we herein report a 28-year old man, a victim of car-car accident who was brought to our surgical emergency room by immediate loss of co...