نتایج جستجو برای: transplacental
تعداد نتایج: 1342 فیلتر نتایج به سال:
Despite the increasing evidence of human papillomavirus (HPV) vertical transmission, this route is regarded as less clinically important because of the detections of transient HPV DNA. However, recent studies have provided clear evidence of papillomavirus productive infection in lymphocytes, placenta, and bovine fetal tissue. Furthermore, a model of papillomavirus latency has been recently prop...
Our work has focused on the carcinogenic effects of in utero arsenic exposure in mice. Our data show that a short period of maternal exposure to inorganic arsenic in the drinking water is an effective, multi-tissue carcinogen in the adult offspring. These studies have been reproduced in three temporally separate studies using two different mouse strains. In these studies pregnant mice were trea...
Peripheral blood lymphocyte levels attained in adult rats that had been thymectomized at birth were markedly reduced if the two or three immediately preceding generations of rats from which they were bred had been thymectomized as neonates. The capacity of thymectomized animals to survive to adult life was also drastically reduced if they were bred from thymectomized stock. Pregnancy as a resul...
Despite high level of vaccination coverage, pertussis remains a serious problem modern medicine. Pertussis cases are registered among infants, adolescents, and adults. Infants younger than three months age have the highest rate clinical course. Transplacental transfer pertussis-specific antibodies induce protection against infection. The available data regarding anti-pertussis antibody in pregn...
Our previous work has shown that exposure to inorganic arsenic in utero produces hepatocellular carcinoma (HCC) in adult male mice. To explore further the molecular mechanisms of transplacental arsenic hepatocarcinogenesis, we conducted a second arsenic transplacental carcinogenesis study and used a genomewide microarray to profile arsenic-induced aberrant gene expression more extensively. Brie...
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