Holothurian glycosaminoglycan (hGAG) is a high-molecular-weight form of fucosylated chondroitin sulfate and has an antithrombotic effect. Our previous studies demonstrated that hGAG efficiently inhibited tumor cell metastasis. The interplays between thrombosis and tumor progression may have a major impact on hematogenous metastasis. In this study, we demonstrated that the mouse melanoma B16F10 ...

Arid and semiarid environments of Mediterranean countries suffer from scarcity water resources, which limits their agriculture productivity. Using treated wastewater (TWW) is considered an alternative strategy for irrigation purposes in such areas. However, TWW contains substantial levels heavy metals (HMs) contaminants that pollute the environment soil. The aim this study to evaluate phytoreme...

In this paper, a possible use of white sweet clover (Melilotus albus Med.) for phytoremediation was assessed. The plants were grown on soils with naturally occurring concentrations potentially toxic elements (PTEs). First, the content PTEs determined in plant biomass and soil samples using: (a) Optical emission spectrometry inductively coupled plasma to determine Sb, As, Cd, Cu, Ni, Pb, Se, (b)...

Muscle contraction relies on the interaction of myosin motors with F-actin, which is regulated through a translocation of tropomyosin by the troponin complex in response to Ca2+ The current model of muscle regulation holds that at relaxing (low-Ca2+) conditions tropomyosin blocks myosin binding sites on F-actin, whereas at activating (high-Ca2+) conditions tropomyosin translocation only partial...

as a result of human activities, metal pollution has become one of the most serious environmental problems today. phytoremediation utilizes plants to uptake contaminants and can potentially be used to remediate metal-contaminated sites. a pot experiment was conducted to compare the phytoextraction and phytostabilization potential of two plant species (populus alba and morus alba) for some eleme...

CD43 (leukosialin, sialophorin), an abundant leukocyte surface sialoglycoprotein, regulates leukocyte adhesion and transmits activating signals in T cells and dendritic cells. Immobilized anti-CD43 monoclonal antibody (mAb) MEM-59 has been previously shown to induce apoptosis of hematopoietic progenitors. In this study we show that it also triggers apoptosis of the myeloid progenitor-derived ce...

Activation of factor IX in an umbilical vein model was established to result solely from factor VIIa/tissue factor (TF) activity generated within the umbilical vein wall, and the model was then used to study regulation of such extravascular factor VIIa-TF complexes. Vein segments were filled with a reaction mixture containing factor VIIa, Ca2+, a substrate, either [3H]factor IX or [3H]factor X,...

This study was focused on removal of various parameters in paper mill effluent using a method called bioremediation by Azolla caroliniana.  The experimental investigations have been carried out using Azolla caroliniana for conducting the sorption study with various dilution ratios (2, 4, 6, 8, and 10), pH (3, 4, 5, 6, 7, 8 and 9) and biomass (200, 400, 600, 800 and 1000 g). Th...

HIV infection is associated with an increased risk of thrombosis; and as antiretroviral therapy has increased the lifespan of HIV-infected patients, their risk for cardiovascular events is expected to increase. A large clinical study found recently that all-cause mortality for HIV(+) patients was related to plasma levels of interleukin-6 and to D-dimer products of fibrinolysis. We provide evide...

Mining activities, ore concentrations, and transport processes generate large amounts of pollutants, including hazardous elements, which are released into the environment. This work presents results experimental research aimed at evaluating environmental risks soil plant contamination in two magnesite mining processing areas Slovak Republic, assesses phytoremediation potential dominant species....