Volume 4 • Issue 3 • 1000217 Pharmaceut Anal Acta ISSN: 2153-2435 PAA, an open access journal *Corresponding author: Wen-sheng Zheng, Institute of Materia Medica, Chinese Academy of Medical Sciences& Peking Union Medical College, Beijing City Key Laboratory of Drug Delivery Technology and Novel Formulations, Beijing 100050, People’s Republic of China, Tel: +86 010 63165233; Fax: +86 010 6301775...

The aim of the present study was to investigate transfersomes as a transdermal delivery system for the poorly soluble drug, sertraline, in order to overcome the troubles associated with its oral delivery. Different transfersomal formulations were prepared with non-ionic surfactant (span 80), soya lecithin, and carbopol 940 by the rotary evaporation sonication method. The prepared formulations w...

There has been keen interest in the development of a novel drug delivery system. Novel drug delivery system aims to deliver the drug at a rate directed by the needs of the body during the period of treatment, and channel the active entity to the site of action. At present, no available drug delivery system behaves ideally achieving all the lofty goals, but sincere attempts have been made to ach...

The history of using vesicular systems for drug delivery to and through skin started nearly three decades ago with a study utilising phospholipid liposomes to improve skin deposition and reduce systemic effects of triamcinolone acetonide. Subsequently, many researchers evaluated liposomes with respect to skin delivery, with the majority of them recording localised effects and relatively few stu...

Vesicles that are specifically designed to overcome the stratum corneum barrier in intact skin provide an efficient transdermal (systemic or local) drug delivery system. They can be classified into two main groups according to the mechanisms underlying their skin interaction. The first group comprises those possessing highly deformable bilayers, achieved by incorporating edge activators to the ...

Objective: To manage the increasing burden of skin cancer cases globally and to replace conventional invasive treatments their side effects, present study is aimed develop a transfersomal herbal gel Green Tea Catechins (GTC) extracted from indigenous green tea evaluate it for in vivo management an experimental animal model. Methods: GTC-loaded transfersomes (GTCTF) were prepared by thin-film hy...