Serum contains 1-transferrin, and CSF contains 1 and 2 transferrins. The 2-transferrin in CSF is desialylated because of the presence of neuraminidase in the central nervous system. Hence, 2-transferrin is used as a marker of CSF leakage (1 ). Because 1-transferrin was present in serum but absent in drainage fluid, additional neuraminidase activity was suspected. This suspicion was supported by...

approved: Ralph/Bogart Redacted for Privacy A total of 902 plasma samples from the Rambouillet, Targhee, Columbia, Lincoln, and Suffolk breeds of sheep were analyzed for transferrin type by disc electrophoresis. Six transferrin types, TfA, TfB, TfC, Tfp, TfE, and TfP, were found in the Rambouillet, Targhee, and Columbia breeds while five, A, B, C, D, E, and four, A, B, C, D, types were observed...

Rabbit transferrin in vitro is shown to load ferrous iron at random on its specific binding sites. The release of iron to reticulocytes is shown to be an all-or-none phenomenon. The two monoferric transferrins have similar in vivo plasma iron clearance rates and tissue distribution. Diferric transferrin, while giving a similar tissue distribution of radioiron, has a plasma iron clearance rate a...

Two bacterial species with different metabolic features, namely, Pseudomonas aeruginosa and Lactococcus lactis, were used as a comparative experimental model to investigate the antimicrobial target and mechanism of transferrins. In anaerobiosis, P. aeruginosa cells were not susceptible to lactoferrin (hLf) or transferrin (hTf). In aerobiosis, the cells were susceptible but O(2) consumption was ...