Mast cells play pivotal roles in IgE-mediated airway inflammation, expressing interleukin13 (IL-13) and monocyte chemoattracant protein-1 (MCP-1), which in turn regulate IgE synthesis and/or inflammatory cell recruitment. The molecular effects of interleukin-1 beta (IL-1β) on cytokine expression by human mast cells have not been studied well. In this report, we provide evidence that human mast ...
