نتایج جستجو برای: transcriptase

تعداد نتایج: 21795  

Journal: :Journal of Biological Chemistry 1989

Journal: :Nucleic acids research 1993
G Mohr P S Perlman A M Lambowitz

Many group II introns encode reverse transcriptase-like proteins that potentially function in intron mobility and RNA splicing. We compared 34 intron-encoded open reading frames and four related open reading frames that are not encoded in introns. Many of these open reading frames have a reverse transcriptase-like domain, followed by an additional conserved domain X, and a Zn(2+)-finger-like re...

2017
Emel Çalışkan Can M. Can Atalay Ece Miser Salihoğlu Ülkü Yalçıntaş Arslan H. Bolkan Şimşek Sevgi Yardım Akaydın

AIMS To investigate the changes in mRNA expression levels of telomerase-related significant proteins in several types of cancer. METHODS Human telomerase reverse transcriptase, pontin, reptin and dyskerin expressions were measured in normal and tumour tissues obtained from 26 patients with colorectal, breast and gastric cancers, using the real-time reverse transcriptase-polymerase chain react...

Journal: :The Journal of biological chemistry 2001
B Selmi J Boretto J M Navarro J Sire S Longhi C Guerreiro L Mulard S Sarfati B Canard

The amino acid change V75T in human immunodeficiency virus type 1 reverse transcriptase confers a low level of 2',3'-didehydro-2',3'-dideoxythymidine (stavudine, d4T) resistance in vivo and in vitro. Valine 75 is located at the basis of the fingers subdomain of reverse transcriptase between the template contact point and the nucleotide-binding pocket. V75T reverse transcriptase discriminates 3....

Journal: :Proceedings of the National Academy of Sciences 2018

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