Total parenteral nutrition (TPN) impairs small intestine development and is associated with barrier failure, inflammation, and acidomucin goblet cell expansion in neonatal piglets. We examined the relationship between intestinal goblet cell expansion and molecular and cellular indices of inflammation in neonatal piglets receiving TPN, 80% parenteral + 20% enteral nutrition (PEN), or 100% entera...

OBJECTIVE To assess the difference between early enteral nutrition (EEN group) and total parenteral nutrition (TPN group) after total gastrectomy for gastric cancer. METHOD The nutrition index, liver function, patient generated subjective global assessment (PG-SGA) score, the post-operation complications, the hospital stay and hospitalization expense of the postoperative patient after total g...

OBJECTIVE To determine how weight for gestational age affects urea and mineral excretion by preterm infants receiving total parenteral nutrition (TPN). STUDY DESIGN Daily urine samples were collected from all preterm infants given high calcium TPN, providing 30 kcal/g amino acids, during its first 44 months of use, and from all those given standard TPN, providing 25 kcal/g amino acids, over t...

BACKGROUND We undertook this study to test the hypothesis that perioperative total parenteral nutrition (TPN) decreases the incidence of serious complications after major abdominal or thoracic surgical procedures in malnourished patients. METHODS We studied 395 malnourished patients (99 percent of them male) who required laparotomy or noncardiac thoracotomy. They were randomly assigned to rec...

Between amateur passions and a professional academic agenda. The Society of the Friends Learning in Przemyśl as publishing center before 1939 article discusses activity (TPN) from its establishment 1909 until outbreak Second World War 1939. Publishing works was one TPN statutory goals beside e.g. running museum, library, an archive, conducting archaeological work promoting various fields knowle...

parenteral hyperalimentation, all of the patient’s daily nutritional requirements are supplied by infusing nutrients directly into the systemic circulation. TPN is widely employed in a variety of pathophysiological settings for the nutritional support of patients with conditions requiring complete bowel rest (e.g., some stages of Crohn’s disease, ulcerative colitis, and severe pancreatitis) or ...

We report a patient with severe anorexia nervosa, treated with temporary total parenteral nutrition (TPN), in whom reversible hyperintensity of the anterior pituitary gland was seen on T1-weighted MR images. The anterior pituitary was isointense with white matter before TPN therapy and became markedly hyperintense after 3 months of treatment. The intensity normalized after TPN therapy was disco...

1. Purified alkaline phosphatases from cow's milk and calf intestinal mucosa quantitatively convert TPN into DPN. DPN is not hydrolysed by either enzyme. 2. These results confirn that the third phosphate grouping of TPN is esterified (to ribose), since the action of both purified phosphatases is restricted to phospho mono-esters and amides. 3. Under the experimental conditions used, there was n...

A method is described for determining TPN+ and TPNH in a single tissue homogenate made in dilute NaOH at 0’. One portion, for TPN+, is acidified after adding ascorbic acid to prevent TPNH oxidation. A second portion, for TPNH, is heated (still alkaline) after adding cysteine to prevent oxidation. If desired, a third portion can be analyzed directly without heating for total TPN (TPN+ plus TPNH)...

BACKGROUND ATP-sensitive potassium (K(ATP)) channel openers provide cardioprotection in multiple models. Ion flux at an unidentified mitochondrial K(ATP) channel has been proposed as the mechanism. The renal outer medullary kidney potassium channel subunit, potassium inward rectifying (Kir)1.1, has been implicated as a mitochondrial channel pore-forming subunit. We hypothesized that subunit Kir...