pseudomonas aeruginosa as an opportunistic pathogen produces several virulence factors. the most important of these factors are exotoxin a and type iii secretion system (t3ss). the aim of this study was to determine the frequency of toxa, exou and exos genes among clinical isolates of p. aeruginosa. in this cross-sectional study from september 2011 to february 2012, 156 p. aeruginosa isolates w...

Tumor-targeted Salmonella VNP20009 preferentially replicate within tumor tissue and partially suppress tumor growth in murine tumor models. These Salmonella have the ability to locally induce apoptosis when they are in direct contact with cancer cells but they lack significant bystander killing, which may correlate with their overall lack of antitumor activity in human clinical studies. In orde...

Our project is to measure differential responses of various alien cytoplasms in a specific nuclear background to various pathogens to provide a better understanding on the effect of nuclear-cytoplasmic interactions on biotic stress tolerance. In this study, we analyzed the nuclear donors of 56-1 (tetraploid), and Chris and Selkirk (both hexaploid), alloplasmic lines. Fifty selected alloplasmic ...

This investigation's goal was to find Pseudomonas aeruginosa virulence factors in canine wound infections. 100 samples were gathered and tested for eight variables utilizing biochemical molecular techniques this purpose. According the findings, women (72%) had highest isolation ratio. The found various ratios, with capsule being (16.6%) of them, amylase enzyme detected (3.3%), hemolysin (70%), ...

Pseudomonas aeruginosa exotoxin A (PA), a potent protein synthesis inhibitor, was found to be a weak T-cell mitogen for murine splenocytes. Maximal stimulation of [3H]thymidine incorporation was obtained with 10 to 100 ng of toxin per ml following a 4-day induction. PA was also shown to be a polyclonal activator of cytolytic T lymphocytes (CTL), effective against concanavalin A-treated target c...

Most of the heat-labile enterotoxin (LT) synthesized by Escherichia coli is cell associated; however, a small portion of LT (approximately 10%) is released by bacterial cells into the culture supernatant. The LT subunit B (LT-B) produced by a cloned LT-B gene (tox B) was released in amounts equal to the parent LT release. In contrast, no release of LT subunit A (LT-A) or its smaller derivatives...

in this study, to increase information about the relationship between caprine and ovine isolates of pasteurella multocida, 16s rrna gene sequencing of 9 goats (5) and sheep (4) isolates were investigated. also, capsular type and toxagene presentation was studied in this paper. all isolates, except one, belong to capsular type a, and toxa+ strain distributed among strains were isolated from both...